Cochlear outer hair cells in a dominant-negative connexin26 mutant mouse preserve non-linear capacitance in spite of impaired distortion product otoacoustic emission.
Minekawa A, Abe T, Inoshita A, Iizuka T, Kakehata S, Narui Y, Koike T, Kamiya K, Okamura HO, Shinkawa H, Ikeda K.
Minekawa A, et al. Among authors: inoshita a.
Neuroscience. 2009 Dec 15;164(3):1312-9. doi: 10.1016/j.neuroscience.2009.08.043. Epub 2009 Aug 25.
Neuroscience. 2009.
PMID: 19712724
Transgenic mice were established carrying human Cx26 with the R75W mutation that was identified in a deaf family with autosomal dominant negative inheritance [Kudo T et al. (2003) Hum Mol Genet 12:995-1004]. A dominant-negative Gjb2 R75W transgenic mouse model shows …
Transgenic mice were established carrying human Cx26 with the R75W mutation that was identified in a deaf family with autosomal domin …