Barford D - Search Results

1

Multiple factors confer specific Cdc42 and Rac protein activation by dedicator of cytokinesis (DOCK) nucleotide exchange factors.

Kulkarni K, Yang J, Zhang Z, Barford D. Kulkarni K, et al. Among authors: barford d. J Biol Chem. 2011 Jul 15;286(28):25341-51. doi: 10.1074/jbc.M111.236455. Epub 2011 May 24. J Biol Chem. 2011. PMID: 21613211 Free PMC article.

2

Small molecule interactions with protein-tyrosine phosphatase PTP1B and their use in inhibitor design.

Burke TR Jr, Ye B, Yan X, Wang S, Jia Z, Chen L, Zhang ZY, Barford D. Burke TR Jr, et al. Among authors: barford d. Biochemistry. 1996 Dec 17;35(50):15989-96. doi: 10.1021/bi961256d. Biochemistry. 1996. PMID: 8973169

3

Crystal structure of the M-fragment of alpha-catenin: implications for modulation of cell adhesion.

Yang J, Dokurno P, Tonks NK, Barford D. Yang J, et al. Among authors: barford d. EMBO J. 2001 Jul 16;20(14):3645-56. doi: 10.1093/emboj/20.14.3645. EMBO J. 2001. PMID: 11447106 Free PMC article.

4

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation.

Yang J, Cron P, Thompson V, Good VM, Hess D, Hemmings BA, Barford D. Yang J, et al. Among authors: barford d. Mol Cell. 2002 Jun;9(6):1227-40. doi: 10.1016/s1097-2765(02)00550-6. Mol Cell. 2002. PMID: 12086620 Free article.

5

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP.

Yang J, Cron P, Good VM, Thompson V, Hemmings BA, Barford D. Yang J, et al. Among authors: barford d. Nat Struct Biol. 2002 Dec;9(12):940-4. doi: 10.1038/nsb870. Nat Struct Biol. 2002. PMID: 12434148

6

Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.

Yang J, Roe SM, Cliff MJ, Williams MA, Ladbury JE, Cohen PT, Barford D. Yang J, et al. Among authors: barford d. EMBO J. 2005 Jan 12;24(1):1-10. doi: 10.1038/sj.emboj.7600496. Epub 2004 Dec 2. EMBO J. 2005. PMID: 15577939 Free PMC article.

7

Reversible oxidation of the membrane distal domain of receptor PTPalpha is mediated by a cyclic sulfenamide.

Yang J, Groen A, Lemeer S, Jans A, Slijper M, Roe SM, den Hertog J, Barford D. Yang J, et al. Among authors: barford d. Biochemistry. 2007 Jan 23;46(3):709-19. doi: 10.1021/bi061546m. Biochemistry. 2007. PMID: 17223692

8

The structure of Tap42/alpha4 reveals a tetratricopeptide repeat-like fold and provides insights into PP2A regulation.

Yang J, Roe SM, Prickett TD, Brautigan DL, Barford D. Yang J, et al. Among authors: barford d. Biochemistry. 2007 Jul 31;46(30):8807-15. doi: 10.1021/bi7007118. Epub 2007 Jul 6. Biochemistry. 2007. PMID: 17616149

9

Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting.

Plaza-Menacho I, Mologni L, Sala E, Gambacorti-Passerini C, Magee AI, Links TP, Hofstra RM, Barford D, Isacke CM. Plaza-Menacho I, et al. Among authors: barford d. J Biol Chem. 2007 Oct 5;282(40):29230-40. doi: 10.1074/jbc.M703461200. Epub 2007 Jul 30. J Biol Chem. 2007. PMID: 17664273 Free article.

10

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.

Komander D, Patel M, Laurin M, Fradet N, Pelletier A, Barford D, Côté JF. Komander D, et al. Among authors: barford d. Mol Biol Cell. 2008 Nov;19(11):4837-51. doi: 10.1091/mbc.e08-04-0345. Epub 2008 Sep 3. Mol Biol Cell. 2008. PMID: 18768751 Free PMC article.

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