Ernst OP - Search Results

1

G protein-coupled receptor modulation with pepducins: moving closer to the clinic.

Dimond P, Carlson K, Bouvier M, Gerard C, Xu L, Covic L, Agarwal A, Ernst OP, Janz JM, Schwartz TW, Gardella TJ, Milligan G, Kuliopulos A, Sakmar TP, Hunt SW 3rd. Dimond P, et al. Among authors: ernst op. Ann N Y Acad Sci. 2011 May;1226:34-49. doi: 10.1111/j.1749-6632.2011.06039.x. Ann N Y Acad Sci. 2011. PMID: 21615752

2

Structural biology: Ion channel in the spotlight.

Ernst OP, Sakmar TP. Ernst OP, et al. Nature. 2012 Feb 15;482(7385):318-9. doi: 10.1038/482318a. Nature. 2012. PMID: 22337049 No abstract available.

3

Characterization of rhodopsin mutants that bind transducin but fail to induce GTP nucleotide uptake. Classification of mutant pigments by fluorescence, nucleotide release, and flash-induced light-scattering assays.

Ernst OP, Hofmann KP, Sakmar TP. Ernst OP, et al. J Biol Chem. 1995 May 5;270(18):10580-6. doi: 10.1074/jbc.270.18.10580. J Biol Chem. 1995. PMID: 7737995 Free article.

4

Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits.

Ernst OP, Meyer CK, Marin EP, Henklein P, Fu WY, Sakmar TP, Hofmann KP. Ernst OP, et al. J Biol Chem. 2000 Jan 21;275(3):1937-43. doi: 10.1074/jbc.275.3.1937. J Biol Chem. 2000. PMID: 10636895 Free article.

5

A G protein-coupled receptor at work: the rhodopsin model.

Hofmann KP, Scheerer P, Hildebrand PW, Choe HW, Park JH, Heck M, Ernst OP. Hofmann KP, et al. Among authors: ernst op. Trends Biochem Sci. 2009 Nov;34(11):540-52. doi: 10.1016/j.tibs.2009.07.005. Epub 2009 Oct 21. Trends Biochem Sci. 2009. PMID: 19836958 Review.

6

Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit.

Ernst OP, Gramse V, Kolbe M, Hofmann KP, Heck M. Ernst OP, et al. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10859-64. doi: 10.1073/pnas.0701967104. Epub 2007 Jun 19. Proc Natl Acad Sci U S A. 2007. PMID: 17578920 Free PMC article.

7

Molecular assembly of rhodopsin with G protein-coupled receptor kinases.

He Y, Gao X, Goswami D, Hou L, Pal K, Yin Y, Zhao G, Ernst OP, Griffin P, Melcher K, Xu HE. He Y, et al. Among authors: ernst op. Cell Res. 2017 Jun;27(6):728-747. doi: 10.1038/cr.2017.72. Epub 2017 May 19. Cell Res. 2017. PMID: 28524165 Free PMC article.

8

Proton transfer reactions linked to rhodopsin activation.

Szundi I, Mah TL, Lewis JW, Jäger S, Ernst OP, Hofmann KP, Kliger DS. Szundi I, et al. Among authors: ernst op. Biochemistry. 1998 Oct 6;37(40):14237-44. doi: 10.1021/bi981249k. Biochemistry. 1998. PMID: 9760262

9

Molecular motions and hydration of purple membranes and disk membranes studied by neutron scattering.

Fitter J, Ernst OP, Hauss T, Lechner RE, Hofmann KP, Dencher NA. Fitter J, et al. Among authors: ernst op. Eur Biophys J. 1998;27(6):638-45. doi: 10.1007/s002490050175. Eur Biophys J. 1998. PMID: 9791944

10

Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding.

Bayburt TH, Vishnivetskiy SA, McLean MA, Morizumi T, Huang CC, Tesmer JJ, Ernst OP, Sligar SG, Gurevich VV. Bayburt TH, et al. Among authors: ernst op. J Biol Chem. 2011 Jan 14;286(2):1420-8. doi: 10.1074/jbc.M110.151043. Epub 2010 Oct 21. J Biol Chem. 2011. PMID: 20966068 Free PMC article.

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