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Contribution of human papilloma virus to the incidence of squamous cell carcinoma of the head and neck in a European population with high smoking prevalence.
Tinhofer I, Jöhrens K, Keilholz U, Kaufmann A, Lehmann A, Weichert W, Stenzinger A, Stromberger C, Klinghammer K, Becker ET, Dommerich S, Stölzel K, Hofmann VM, Hildebrandt B, Moser L, Ervens J, Böttcher A, Albers A, Stabenow R, Reinecke A, Budach V, Hoffmeister B, Raguse JD. Tinhofer I, et al. Among authors: klinghammer k. Eur J Cancer. 2015 Mar;51(4):514-521. doi: 10.1016/j.ejca.2014.12.018. Epub 2015 Jan 23. Eur J Cancer. 2015. PMID: 25623438
Methylation of RAD51B, XRCC3 and other homologous recombination genes is associated with expression of immune checkpoints and an inflammatory signature in squamous cell carcinoma of the head and neck, lung and cervix.
Rieke DT, Ochsenreither S, Klinghammer K, Seiwert TY, Klauschen F, Tinhofer I, Keilholz U. Rieke DT, et al. Among authors: klinghammer k. Oncotarget. 2016 Nov 15;7(46):75379-75393. doi: 10.18632/oncotarget.12211. Oncotarget. 2016. PMID: 27683114 Free PMC article.
Targeted Therapy of Head and Neck Cancer.
Rieke DT, Klinghammer K, Keilholz U. Rieke DT, et al. Among authors: klinghammer k. Oncol Res Treat. 2016;39(12):780-786. doi: 10.1159/000452432. Epub 2016 Nov 22. Oncol Res Treat. 2016. PMID: 27889751 Review.
First-in-man dose escalation and pharmacokinetic study of CAP7.1, a novel prodrug of etoposide, in adults with refractory solid tumours.
Keilholz U, Rohde L, Mehlitz P, Knoedler M, Schmittel A, Kümmerlen V, Klinghammer K, Treasure P, Lassus M, Steventon G, Machacek M, Utku N. Keilholz U, et al. Among authors: klinghammer k. Eur J Cancer. 2017 Jul;80:14-25. doi: 10.1016/j.ejca.2017.03.032. Epub 2017 May 19. Eur J Cancer. 2017. PMID: 28531881 Clinical Trial.
Cetuximab, fluorouracil and cisplatin with or without docetaxel for patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (CeFCiD): an open-label phase II randomised trial (AIO/IAG-KHT trial 1108).
Klinghammer K, Gauler T, Dietz A, Grünwald V, Stöhlmacher J, Knipping S, Schroeder M, Guntinas-Lichius O, Frickhofen N, Lindeman HW, Fietkau R, Haxel B, Große-Thie C, Maschmeyer G, Zipfel M, Martus P, Knoedler M, Keilholz U. Klinghammer K, et al. Eur J Cancer. 2019 Nov;122:53-60. doi: 10.1016/j.ejca.2019.08.018. Epub 2019 Oct 13. Eur J Cancer. 2019. PMID: 31618704 Clinical Trial.
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