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The transient receptor potential (TRP) channel TRPC3 TRP domain and AMP-activated protein kinase binding site are required for TRPC3 activation by erythropoietin.
Hirschler-Laszkiewicz I, Tong Q, Waybill K, Conrad K, Keefer K, Zhang W, Chen SJ, Cheung JY, Miller BA. Hirschler-Laszkiewicz I, et al. Among authors: conrad k. J Biol Chem. 2011 Sep 2;286(35):30636-30646. doi: 10.1074/jbc.M111.238360. Epub 2011 Jul 14. J Biol Chem. 2011. PMID: 21757714 Free PMC article.
TRPC3 activation by erythropoietin is modulated by TRPC6.
Hirschler-Laszkiewicz I, Tong Q, Conrad K, Zhang W, Flint WW, Barber AJ, Barber DL, Cheung JY, Miller BA. Hirschler-Laszkiewicz I, et al. Among authors: conrad k. J Biol Chem. 2009 Feb 13;284(7):4567-81. doi: 10.1074/jbc.M804734200. Epub 2008 Dec 13. J Biol Chem. 2009. PMID: 19074769 Free PMC article.
Trpc2 depletion protects red blood cells from oxidative stress-induced hemolysis.
Hirschler-Laszkiewicz I, Zhang W, Keefer K, Conrad K, Tong Q, Chen SJ, Bronson S, Cheung JY, Miller BA. Hirschler-Laszkiewicz I, et al. Among authors: conrad k. Exp Hematol. 2012 Jan;40(1):71-83. doi: 10.1016/j.exphem.2011.09.006. Epub 2011 Sep 14. Exp Hematol. 2012. PMID: 21924222 Free PMC article.
A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.
Chen SJ, Hoffman NE, Shanmughapriya S, Bao L, Keefer K, Conrad K, Merali S, Takahashi Y, Abraham T, Hirschler-Laszkiewicz I, Wang J, Zhang XQ, Song J, Barrero C, Shi Y, Kawasawa YI, Bayerl M, Sun T, Barbour M, Wang HG, Madesh M, Cheung JY, Miller BA. Chen SJ, et al. Among authors: conrad k. J Biol Chem. 2014 Dec 26;289(52):36284-302. doi: 10.1074/jbc.M114.620922. Epub 2014 Nov 12. J Biol Chem. 2014. PMID: 25391657 Free PMC article.
Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics.
Bao L, Chen SJ, Conrad K, Keefer K, Abraham T, Lee JP, Wang J, Zhang XQ, Hirschler-Laszkiewicz I, Wang HG, Dovat S, Gans B, Madesh M, Cheung JY, Miller BA. Bao L, et al. Among authors: conrad k. J Biol Chem. 2016 Nov 18;291(47):24449-24464. doi: 10.1074/jbc.M116.747147. Epub 2016 Sep 30. J Biol Chem. 2016. PMID: 27694440 Free PMC article.
Erythropoietin modulates calcium influx through TRPC2.
Chu X, Cheung JY, Barber DL, Birnbaumer L, Rothblum LI, Conrad K, Abrasonis V, Chan YM, Stahl R, Carey DJ, Miller BA. Chu X, et al. Among authors: conrad k. J Biol Chem. 2002 Sep 13;277(37):34375-82. doi: 10.1074/jbc.M205541200. Epub 2002 Jul 11. J Biol Chem. 2002. PMID: 12167663 Free article.
663 results