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Gefitinib inhibits the growth and invasion of urothelial carcinoma cell lines in which Akt and MAPK activation is dependent on constitutive epidermal growth factor receptor activation.
Nicolle G, Daher A, Maillé P, Vermey M, Loric S, Bakkar A, Wallerand H, Vordos D, Vacherot F, de Medina SG, Abbou CC, Van der Kwast T, Thiery JP, Radvanyi F, Chopin DK. Nicolle G, et al. Among authors: bakkar a. Clin Cancer Res. 2006 May 1;12(9):2937-43. doi: 10.1158/1078-0432.CCR-05-2148. Clin Cancer Res. 2006. PMID: 16675591
Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: contribution of exogenous versus endogenous carcinogens.
Wallerand H, Bakkar AA, de Medina SG, Pairon JC, Yang YC, Vordos D, Bittard H, Fauconnet S, Kouyoumdjian JC, Jaurand MC, Zhang ZF, Radvanyi F, Thiery JP, Chopin DK. Wallerand H, et al. Among authors: bakkar aa. Carcinogenesis. 2005 Jan;26(1):177-84. doi: 10.1093/carcin/bgh275. Epub 2004 Sep 3. Carcinogenesis. 2005. PMID: 15347601
Occupational exposure to polycyclic aromatic hydrocarbons influenced neither the frequency nor the spectrum of FGFR3 mutations in bladder urothelial carcinoma.
Bakkar AA, Allory Y, Iwatsubo Y, de Medina SG, Maille P, Khreich N, Riou A, Leroy K, Vordos D, Abbou CC, Andujar P, Billebaud T, Chammings S, Conso F, De La Taille A, Fontaine E, Gattegno B, Ravery V, Sibony M, Radvanyi F, Chopin DK, Pairon JC. Bakkar AA, et al. Mol Carcinog. 2010 Jan;49(1):25-31. doi: 10.1002/mc.20573. Mol Carcinog. 2010. PMID: 19722178
A meta-analysis of the relationship between FGFR3 and TP53 mutations in bladder cancer.
Neuzillet Y, Paoletti X, Ouerhani S, Mongiat-Artus P, Soliman H, de The H, Sibony M, Denoux Y, Molinie V, Herault A, Lepage ML, Maille P, Renou A, Vordos D, Abbou CC, Bakkar A, Asselain B, Kourda N, El Gaaied A, Leroy K, Laplanche A, Benhamou S, Lebret T, Allory Y, Radvanyi F. Neuzillet Y, et al. Among authors: bakkar a. PLoS One. 2012;7(12):e48993. doi: 10.1371/journal.pone.0048993. Epub 2012 Dec 13. PLoS One. 2012. PMID: 23272046 Free PMC article.
48 results