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Optimization of humanized IgGs in glycoengineered Pichia pastoris.
Li H, Sethuraman N, Stadheim TA, Zha D, Prinz B, Ballew N, Bobrowicz P, Choi BK, Cook WJ, Cukan M, Houston-Cummings NR, Davidson R, Gong B, Hamilton SR, Hoopes JP, Jiang Y, Kim N, Mansfield R, Nett JH, Rios S, Strawbridge R, Wildt S, Gerngross TU. Li H, et al. Among authors: jiang y. Nat Biotechnol. 2006 Feb;24(2):210-5. doi: 10.1038/nbt1178. Epub 2006 Jan 22. Nat Biotechnol. 2006. PMID: 16429149
Production of monoclonal antibodies by glycoengineered Pichia pastoris.
Potgieter TI, Cukan M, Drummond JE, Houston-Cummings NR, Jiang Y, Li F, Lynaugh H, Mallem M, McKelvey TW, Mitchell T, Nylen A, Rittenhour A, Stadheim TA, Zha D, d'Anjou M. Potgieter TI, et al. Among authors: jiang y. J Biotechnol. 2009 Feb 23;139(4):318-25. doi: 10.1016/j.jbiotec.2008.12.015. Epub 2008 Dec 27. J Biotechnol. 2009. PMID: 19162096
Binding of DC-SIGN to glycoproteins expressed in glycoengineered Pichia pastoris.
Cukan MC, Hopkins D, Burnina I, Button M, Giaccone E, Houston-Cummings NR, Jiang Y, Li F, Mallem M, Mitchell T, Moore R, Nylen A, Prinz B, Rios S, Sharkey N, Zha D, Hamilton S, Li H, Stadheim TA. Cukan MC, et al. Among authors: jiang y. J Immunol Methods. 2012 Dec 14;386(1-2):34-42. doi: 10.1016/j.jim.2012.08.015. Epub 2012 Sep 14. J Immunol Methods. 2012. PMID: 22982058
Humanization of yeast to produce complex terminally sialylated glycoproteins.
Hamilton SR, Davidson RC, Sethuraman N, Nett JH, Jiang Y, Rios S, Bobrowicz P, Stadheim TA, Li H, Choi BK, Hopkins D, Wischnewski H, Roser J, Mitchell T, Strawbridge RR, Hoopes J, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: jiang y. Science. 2006 Sep 8;313(5792):1441-3. doi: 10.1126/science.1130256. Science. 2006. PMID: 16960007
High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies.
Barnard GC, Kull AR, Sharkey NS, Shaikh SS, Rittenhour AM, Burnina I, Jiang Y, Li F, Lynaugh H, Mitchell T, Nett JH, Nylen A, Potgieter TI, Prinz B, Rios SE, Zha D, Sethuraman N, Stadheim TA, Bobrowicz P. Barnard GC, et al. Among authors: jiang y. J Ind Microbiol Biotechnol. 2010 Sep;37(9):961-71. doi: 10.1007/s10295-010-0746-1. Epub 2010 Aug 15. J Ind Microbiol Biotechnol. 2010. PMID: 20711797
Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study.
Zhang N, Liu L, Dumitru CD, Cummings NR, Cukan M, Jiang Y, Li Y, Li F, Mitchell T, Mallem MR, Ou Y, Patel RN, Vo K, Wang H, Burnina I, Choi BK, Huber HE, Stadheim TA, Zha D. Zhang N, et al. Among authors: jiang y. MAbs. 2011 May-Jun;3(3):289-98. doi: 10.4161/mabs.3.3.15532. Epub 2011 May 1. MAbs. 2011. PMID: 21487242 Free PMC article.
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