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Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: production of complex humanized glycoproteins with terminal galactose.
Bobrowicz P, Davidson RC, Li H, Potgieter TI, Nett JH, Hamilton SR, Stadheim TA, Miele RG, Bobrowicz B, Mitchell T, Rausch S, Renfer E, Wildt S. Bobrowicz P, et al. Among authors: mitchell t. Glycobiology. 2004 Sep;14(9):757-66. doi: 10.1093/glycob/cwh104. Epub 2004 Jun 9. Glycobiology. 2004. PMID: 15190003
Production of monoclonal antibodies by glycoengineered Pichia pastoris.
Potgieter TI, Cukan M, Drummond JE, Houston-Cummings NR, Jiang Y, Li F, Lynaugh H, Mallem M, McKelvey TW, Mitchell T, Nylen A, Rittenhour A, Stadheim TA, Zha D, d'Anjou M. Potgieter TI, et al. Among authors: mitchell t. J Biotechnol. 2009 Feb 23;139(4):318-25. doi: 10.1016/j.jbiotec.2008.12.015. Epub 2008 Dec 27. J Biotechnol. 2009. PMID: 19162096
Elimination of β-mannose glycan structures in Pichia pastoris.
Hopkins D, Gomathinayagam S, Rittenhour AM, Du M, Hoyt E, Karaveg K, Mitchell T, Nett JH, Sharkey NJ, Stadheim TA, Li H, Hamilton SR. Hopkins D, et al. Among authors: mitchell t. Glycobiology. 2011 Dec;21(12):1616-26. doi: 10.1093/glycob/cwr108. Epub 2011 Aug 12. Glycobiology. 2011. PMID: 21840970
Optimization of erythropoietin production with controlled glycosylation-PEGylated erythropoietin produced in glycoengineered Pichia pastoris.
Nett JH, Gomathinayagam S, Hamilton SR, Gong B, Davidson RC, Du M, Hopkins D, Mitchell T, Mallem MR, Nylen A, Shaikh SS, Sharkey N, Barnard GC, Copeland V, Liu L, Evers R, Li Y, Gray PM, Lingham RB, Visco D, Forrest G, DeMartino J, Linden T, Potgieter TI, Wildt S, Stadheim TA, d'Anjou M, Li H, Sethuraman N. Nett JH, et al. Among authors: mitchell t. J Biotechnol. 2012 Jan;157(1):198-206. doi: 10.1016/j.jbiotec.2011.11.002. Epub 2011 Nov 9. J Biotechnol. 2012. PMID: 22100268
Binding of DC-SIGN to glycoproteins expressed in glycoengineered Pichia pastoris.
Cukan MC, Hopkins D, Burnina I, Button M, Giaccone E, Houston-Cummings NR, Jiang Y, Li F, Mallem M, Mitchell T, Moore R, Nylen A, Prinz B, Rios S, Sharkey N, Zha D, Hamilton S, Li H, Stadheim TA. Cukan MC, et al. Among authors: mitchell t. J Immunol Methods. 2012 Dec 14;386(1-2):34-42. doi: 10.1016/j.jim.2012.08.015. Epub 2012 Sep 14. J Immunol Methods. 2012. PMID: 22982058
Intact {alpha}-1,2-endomannosidase is a typical type II membrane protein.
Hamilton SR, Li H, Wischnewski H, Prasad A, Kerley-Hamilton JS, Mitchell T, Walling AJ, Davidson RC, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: mitchell t. Glycobiology. 2005 Jun;15(6):615-24. doi: 10.1093/glycob/cwi045. Epub 2005 Jan 26. Glycobiology. 2005. PMID: 15677381
Humanization of yeast to produce complex terminally sialylated glycoproteins.
Hamilton SR, Davidson RC, Sethuraman N, Nett JH, Jiang Y, Rios S, Bobrowicz P, Stadheim TA, Li H, Choi BK, Hopkins D, Wischnewski H, Roser J, Mitchell T, Strawbridge RR, Hoopes J, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: mitchell t. Science. 2006 Sep 8;313(5792):1441-3. doi: 10.1126/science.1130256. Science. 2006. PMID: 16960007
2,040 results