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Page 1
Optimization of humanized IgGs in glycoengineered Pichia pastoris.
Li H, Sethuraman N, Stadheim TA, Zha D, Prinz B, Ballew N, Bobrowicz P, Choi BK, Cook WJ, Cukan M, Houston-Cummings NR, Davidson R, Gong B, Hamilton SR, Hoopes JP, Jiang Y, Kim N, Mansfield R, Nett JH, Rios S, Strawbridge R, Wildt S, Gerngross TU. Li H, et al. Among authors: sethuraman n. Nat Biotechnol. 2006 Feb;24(2):210-5. doi: 10.1038/nbt1178. Epub 2006 Jan 22. Nat Biotechnol. 2006. PMID: 16429149
Purification process development of a recombinant monoclonal antibody expressed in glycoengineered Pichia pastoris.
Jiang Y, Li F, Zha D, Potgieter TI, Mitchell T, Moore R, Cukan M, Houston-Cummings NR, Nylen A, Drummond JE, McKelvey TW, d'Anjou M, Stadheim TA, Sethuraman N, Li H. Jiang Y, et al. Among authors: sethuraman n. Protein Expr Purif. 2011 Mar;76(1):7-14. doi: 10.1016/j.pep.2010.11.004. Epub 2010 Nov 11. Protein Expr Purif. 2011. PMID: 21074617
Challenges in therapeutic glycoprotein production.
Sethuraman N, Stadheim TA. Sethuraman N, et al. Curr Opin Biotechnol. 2006 Aug;17(4):341-6. doi: 10.1016/j.copbio.2006.06.010. Epub 2006 Jul 7. Curr Opin Biotechnol. 2006. PMID: 16828275 Review.
Humanization of yeast to produce complex terminally sialylated glycoproteins.
Hamilton SR, Davidson RC, Sethuraman N, Nett JH, Jiang Y, Rios S, Bobrowicz P, Stadheim TA, Li H, Choi BK, Hopkins D, Wischnewski H, Roser J, Mitchell T, Strawbridge RR, Hoopes J, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: sethuraman n. Science. 2006 Sep 8;313(5792):1441-3. doi: 10.1126/science.1130256. Science. 2006. PMID: 16960007
High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies.
Barnard GC, Kull AR, Sharkey NS, Shaikh SS, Rittenhour AM, Burnina I, Jiang Y, Li F, Lynaugh H, Mitchell T, Nett JH, Nylen A, Potgieter TI, Prinz B, Rios SE, Zha D, Sethuraman N, Stadheim TA, Bobrowicz P. Barnard GC, et al. Among authors: sethuraman n. J Ind Microbiol Biotechnol. 2010 Sep;37(9):961-71. doi: 10.1007/s10295-010-0746-1. Epub 2010 Aug 15. J Ind Microbiol Biotechnol. 2010. PMID: 20711797
Optimization of erythropoietin production with controlled glycosylation-PEGylated erythropoietin produced in glycoengineered Pichia pastoris.
Nett JH, Gomathinayagam S, Hamilton SR, Gong B, Davidson RC, Du M, Hopkins D, Mitchell T, Mallem MR, Nylen A, Shaikh SS, Sharkey N, Barnard GC, Copeland V, Liu L, Evers R, Li Y, Gray PM, Lingham RB, Visco D, Forrest G, DeMartino J, Linden T, Potgieter TI, Wildt S, Stadheim TA, d'Anjou M, Li H, Sethuraman N. Nett JH, et al. Among authors: sethuraman n. J Biotechnol. 2012 Jan;157(1):198-206. doi: 10.1016/j.jbiotec.2011.11.002. Epub 2011 Nov 9. J Biotechnol. 2012. PMID: 22100268
Inactivation of a GAL4-like transcription factor improves cell fitness and product yield in glycoengineered Pichia pastoris strains.
Jiang B, Argyros R, Bukowski J, Nelson S, Sharkey N, Kim S, Copeland V, Davidson RC, Chen R, Zhuang J, Sethuraman N, Stadheim TA. Jiang B, et al. Among authors: sethuraman n. Appl Environ Microbiol. 2015 Jan;81(1):260-71. doi: 10.1128/AEM.02619-14. Epub 2014 Oct 24. Appl Environ Microbiol. 2015. PMID: 25344235 Free PMC article.
52 results