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Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15.
Haraguchi K, Suzuki T, Koyama N, Kumano K, Nakahara F, Matsumoto A, Yokoyama Y, Sakata-Yanagimoto M, Masuda S, Takahashi T, Kamijo A, Takahashi K, Takanashi M, Okuyama Y, Yasutomo K, Sakano S, Yagita H, Kurokawa M, Ogawa S, Chiba S. Haraguchi K, et al. Among authors: koyama n. J Immunol. 2009 May 15;182(10):6168-78. doi: 10.4049/jimmunol.0803036. J Immunol. 2009. PMID: 19414770
IL-18 activates STAT3 in the natural killer cell line 92, augments cytotoxic activity, and mediates IFN-gamma production by the stress kinase p38 and by the extracellular regulated kinases p44erk-1 and p42erk-21.
Kalina U, Kauschat D, Koyama N, Nuernberger H, Ballas K, Koschmieder S, Bug G, Hofmann WK, Hoelzer D, Ottmann OG. Kalina U, et al. Among authors: koyama n. J Immunol. 2000 Aug 1;165(3):1307-13. doi: 10.4049/jimmunol.165.3.1307. J Immunol. 2000. PMID: 10903731
606 results