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Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Mali RS, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, Wei L, Vemula S, Nabinger SC, Goodwin CB, Chan RJ, Traina F, Visconte V, Tiu RV, Lewis TA, Stern AM, Wen Q, Crispino JD, Boswell HS, Kapur R. Mali RS, et al. Among authors: traina f. Cancer Cell. 2011 Sep 13;20(3):357-69. doi: 10.1016/j.ccr.2011.07.016. Cancer Cell. 2011. PMID: 21907926 Free PMC article.
Clofarabine for myelodysplastic syndromes.
Tiu RV, Traina F, Sekeres MA. Tiu RV, et al. Among authors: traina f. Expert Opin Investig Drugs. 2011 Jul;20(7):1005-14. doi: 10.1517/13543784.2011.585967. Epub 2011 May 19. Expert Opin Investig Drugs. 2011. PMID: 21591997 Review.
Updates in cytogenetics and molecular markers in MDS.
Tiu RV, Visconte V, Traina F, Schwandt A, Maciejewski JP. Tiu RV, et al. Among authors: traina f. Curr Hematol Malig Rep. 2011 Jun;6(2):126-35. doi: 10.1007/s11899-011-0081-2. Curr Hematol Malig Rep. 2011. PMID: 21340513 Review.
Familial systemic mastocytosis with germline KIT K509I mutation is sensitive to treatment with imatinib, dasatinib and PKC412.
de Melo Campos P, Machado-Neto JA, Scopim-Ribeiro R, Visconte V, Tabarroki A, Duarte AS, Barra FF, Vassalo J, Rogers HJ, Lorand-Metze I, Tiu RV, Costa FF, Olalla Saad ST, Traina F. de Melo Campos P, et al. Among authors: traina f. Leuk Res. 2014 Oct;38(10):1245-51. doi: 10.1016/j.leukres.2014.07.010. Epub 2014 Aug 1. Leuk Res. 2014. PMID: 25139846 Free article.
Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.
Traina F, Visconte V, Jankowska AM, Makishima H, O'Keefe CL, Elson P, Han Y, Hsieh FH, Sekeres MA, Mali RS, Kalaycio M, Lichtin AE, Advani AS, Duong HK, Copelan E, Kapur R, Olalla Saad ST, Maciejewski JP, Tiu RV. Traina F, et al. PLoS One. 2012;7(8):e43090. doi: 10.1371/journal.pone.0043090. Epub 2012 Aug 15. PLoS One. 2012. PMID: 22905207 Free PMC article.
Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A.
Jankowska AM, Makishima H, Tiu RV, Szpurka H, Huang Y, Traina F, Visconte V, Sugimoto Y, Prince C, O'Keefe C, Hsi ED, List A, Sekeres MA, Rao A, McDevitt MA, Maciejewski JP. Jankowska AM, et al. Among authors: traina f. Blood. 2011 Oct 6;118(14):3932-41. doi: 10.1182/blood-2010-10-311019. Epub 2011 Aug 9. Blood. 2011. PMID: 21828135 Free PMC article.
A case of mistaken identity: When lupus masquerades as primary myelofibrosis.
Hasrouni E, Rogers HJ, Tabarroki A, Visconte V, Traina F, Afable M, Sekeres MA, Maciejewski JP, Tiu RV. Hasrouni E, et al. Among authors: traina f. SAGE Open Med Case Rep. 2013 Aug 20;1:2050313X13498709. doi: 10.1177/2050313X13498709. eCollection 2013. SAGE Open Med Case Rep. 2013. PMID: 27489629 Free PMC article.
Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia.
Kar SA, Jankowska A, Makishima H, Visconte V, Jerez A, Sugimoto Y, Muramatsu H, Traina F, Afable M, Guinta K, Tiu RV, Przychodzen B, Sakaguchi H, Kojima S, Sekeres MA, List AF, McDevitt MA, Maciejewski JP. Kar SA, et al. Among authors: traina f. Haematologica. 2013 Jan;98(1):107-13. doi: 10.3324/haematol.2012.064048. Epub 2012 Jul 6. Haematologica. 2013. PMID: 22773603 Free PMC article.
SF3B1 mutations are infrequently found in non-myelodysplastic bone marrow failure syndromes and mast cell diseases but, if present, are associated with the ring sideroblast phenotype.
Visconte V, Tabarroki A, Rogers HJ, Hasrouni E, Traina F, Makishima H, Hamilton BK, Liu Y, O'Keefe C, Lichtin A, Horwitz L, Sekeres MA, Hsieh FH, Tiu RV. Visconte V, et al. Among authors: traina f. Haematologica. 2013 Sep;98(9):e105-7. doi: 10.3324/haematol.2013.090506. Epub 2013 Jul 5. Haematologica. 2013. PMID: 23831919 Free PMC article. No abstract available.
343 results