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PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance.
Becattini B, Marone R, Zani F, Arsenijevic D, Seydoux J, Montani JP, Dulloo AG, Thorens B, Preitner F, Wymann MP, Solinas G. Becattini B, et al. Among authors: dulloo ag. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):E854-63. doi: 10.1073/pnas.1106698108. Epub 2011 Sep 26. Proc Natl Acad Sci U S A. 2011. PMID: 21949398 Free PMC article.
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