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Epigenetic drug discovery: targeting DNA methyltransferases.
Foulks JM, Parnell KM, Nix RN, Chau S, Swierczek K, Saunders M, Wright K, Hendrickson TF, Ho KK, McCullar MV, Kanner SB. Foulks JM, et al. Among authors: saunders m. J Biomol Screen. 2012 Jan;17(1):2-17. doi: 10.1177/1087057111421212. Epub 2011 Sep 30. J Biomol Screen. 2012. PMID: 21965114 Review.
Pharmacologic activation of PKM2 slows lung tumor xenograft growth.
Parnell KM, Foulks JM, Nix RN, Clifford A, Bullough J, Luo B, Senina A, Vollmer D, Liu J, McCarthy V, Xu Y, Saunders M, Liu XH, Pearce S, Wright K, O'Reilly M, McCullar MV, Ho KK, Kanner SB. Parnell KM, et al. Among authors: saunders m. Mol Cancer Ther. 2013 Aug;12(8):1453-60. doi: 10.1158/1535-7163.MCT-13-0026. Epub 2013 May 29. Mol Cancer Ther. 2013. PMID: 23720766
Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1.
Tardif KD, Rogers A, Cassiano J, Roth BL, Cimbora DM, McKinnon R, Peterson A, Douce TB, Robinson R, Dorweiler I, Davis T, Hess MA, Ostanin K, Papac DI, Baichwal V, McAlexander I, Willardsen JA, Saunders M, Christophe H, Kumar DV, Wettstein DA, Carlson RO, Williams BL. Tardif KD, et al. Among authors: saunders m. Mol Cancer Ther. 2011 Dec;10(12):2267-75. doi: 10.1158/1535-7163.MCT-11-0453. Epub 2011 Oct 6. Mol Cancer Ther. 2011. PMID: 21980130
Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors.
Vijay Kumar D, Hoarau C, Bursavich M, Slattum P, Gerrish D, Yager K, Saunders M, Shenderovich M, Roth BL, McKinnon R, Chan A, Cimbora DM, Bradford C, Reeves L, Patton S, Papac DI, Williams BL, Carlson RO. Vijay Kumar D, et al. Among authors: saunders m. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4377-85. doi: 10.1016/j.bmcl.2012.04.131. Epub 2012 May 5. Bioorg Med Chem Lett. 2012. PMID: 22632936
Triterpene based compounds with potent anti-maturation activity against HIV-1.
Gerrish D, Kim IC, Kumar DV, Austin H, Garrus JE, Baichwal V, Saunders M, McKinnon RS, Anderson MB, Carlson R, Arranz-Plaza E, Yager KM. Gerrish D, et al. Among authors: saunders m. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6377-80. doi: 10.1016/j.bmcl.2008.10.098. Epub 2008 Oct 25. Bioorg Med Chem Lett. 2008. PMID: 18996008
Time From Colorectal Cancer Surgery to Adjuvant Chemotherapy: Post Hoc Analysis of the SCOT Randomized Clinical Trial.
Gögenur M, Rosen AW, Iveson T, Kerr RS, Saunders MP, Cassidy J, Tabernero J, Haydon A, Glimelius B, Harkin A, Allan K, Pearson S, Boyd KA, Briggs AH, Waterston A, Medley L, Ellis R, Dhadda AS, Harrison M, Falk S, Rees C, Olesen RK, Propper D, Bridgewater J, Azzabi A, Cunningham D, Hickish T, Gollins S, Wasan HS, Kelly C, Gögenur I, Holländer NH. Gögenur M, et al. Among authors: saunders mp. JAMA Surg. 2024 Jun 12. doi: 10.1001/jamasurg.2024.1555. Online ahead of print. JAMA Surg. 2024. PMID: 38865139
Lenvatinib Plus Pembrolizumab Versus Standard of Care for Previously Treated Metastatic Colorectal Cancer: Final Analysis of the Randomized, Open-Label, Phase III LEAP-017 Study.
Kawazoe A, Xu RH, García-Alfonso P, Passhak M, Teng HW, Shergill A, Gumus M, Qvortrup C, Stintzing S, Towns K, Kim TW, Shiu KK, Cundom J, Ananda S, Lebedinets A, Fu R, Jain R, Adelberg D, Heinemann V, Yoshino T, Elez E; LEAP-017 Investigators. Kawazoe A, et al. J Clin Oncol. 2024 Jun 4:JCO2302736. doi: 10.1200/JCO.23.02736. Online ahead of print. J Clin Oncol. 2024. PMID: 38833658
Newly Recognized Spotted Fever Group Rickettsia as Cause of Severe Rocky Mountain Spotted Fever-Like Illness, Northern California, USA.
Probert WS, Haw MP, Nichol AC, Glaser CA, Park SY, Campbell LE, Trivedi KK, Romo H, Saunders MEM, Kjemtrup AM, Padgett KA, Hacker JK. Probert WS, et al. Among authors: saunders mem. Emerg Infect Dis. 2024 May 30;30(7). doi: 10.3201/eid3007.231771. Online ahead of print. Emerg Infect Dis. 2024. PMID: 38816345 Free article.
1,689 results