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Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD).
Moffett K, Konteatis Z, Nguyen D, Shetty R, Ludington J, Fujimoto T, Lee KJ, Chai X, Namboodiri H, Karpusas M, Dorsey B, Guarnieri F, Bukhtiyarova M, Springman E, Michelotti E. Moffett K, et al. Among authors: namboodiri h. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7155-65. doi: 10.1016/j.bmcl.2011.09.078. Epub 2011 Sep 28. Bioorg Med Chem Lett. 2011. PMID: 22014550
Creutzfeldt-Jakob Disease Following Kidney Transplantation.
Sharma N, Wang L, Namboodiri H. Sharma N, et al. Among authors: namboodiri h. Cureus. 2022 Jan 26;14(1):e21632. doi: 10.7759/cureus.21632. eCollection 2022 Jan. Cureus. 2022. PMID: 35228978 Free PMC article.
Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent.
Boyd-Shiwarski CR, Shiwarski DJ, Roy A, Namboodiri HN, Nkashama LJ, Xie J, McClain KL, Marciszyn A, Kleyman TR, Tan RJ, Stolz DB, Puthenveedu MA, Huang CL, Subramanya AR. Boyd-Shiwarski CR, et al. Among authors: namboodiri hn. Mol Biol Cell. 2018 Feb 15;29(4):499-509. doi: 10.1091/mbc.E17-08-0529. Epub 2017 Dec 13. Mol Biol Cell. 2018. PMID: 29237822 Free PMC article.