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Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer.
Friedbichler K, Themanns M, Mueller KM, Schlederer M, Kornfeld JW, Terracciano LM, Kozlov AV, Haindl S, Kenner L, Kolbe T, Mueller M, Snibson KJ, Heim MH, Moriggl R. Friedbichler K, et al. Among authors: heim mh. Hepatology. 2012 Mar;55(3):941-52. doi: 10.1002/hep.24765. Epub 2012 Jan 13. Hepatology. 2012. PMID: 22031092
Cleavage of mitochondrial antiviral signaling protein in the liver of patients with chronic hepatitis C correlates with a reduced activation of the endogenous interferon system.
Bellecave P, Sarasin-Filipowicz M, Donzé O, Kennel A, Gouttenoire J, Meylan E, Terracciano L, Tschopp J, Sarrazin C, Berg T, Moradpour D, Heim MH. Bellecave P, et al. Among authors: heim mh. Hepatology. 2010 Apr;51(4):1127-36. doi: 10.1002/hep.23426. Hepatology. 2010. PMID: 20044805
Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.
Mueller KM, Kornfeld JW, Friedbichler K, Blaas L, Egger G, Esterbauer H, Hasselblatt P, Schlederer M, Haindl S, Wagner KU, Engblom D, Haemmerle G, Kratky D, Sexl V, Kenner L, Kozlov AV, Terracciano L, Zechner R, Schuetz G, Casanova E, Pospisilik JA, Heim MH, Moriggl R. Mueller KM, et al. Among authors: heim mh. Hepatology. 2011 Oct;54(4):1398-409. doi: 10.1002/hep.24509. Hepatology. 2011. PMID: 21725989 Free PMC article.
Constitutive Notch2 signaling induces hepatic tumors in mice.
Dill MT, Tornillo L, Fritzius T, Terracciano L, Semela D, Bettler B, Heim MH, Tchorz JS. Dill MT, et al. Among authors: heim mh. Hepatology. 2013 Apr;57(4):1607-19. doi: 10.1002/hep.26165. Epub 2013 Mar 14. Hepatology. 2013. PMID: 23175466
191 results