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Systematic exploration of synergistic drug pairs.
Cokol M, Chua HN, Tasan M, Mutlu B, Weinstein ZB, Suzuki Y, Nergiz ME, Costanzo M, Baryshnikova A, Giaever G, Nislow C, Myers CL, Andrews BJ, Boone C, Roth FP. Cokol M, et al. Mol Syst Biol. 2011 Nov 8;7:544. doi: 10.1038/msb.2011.71. Mol Syst Biol. 2011. PMID: 22068327 Free PMC article.
Large-scale identification and analysis of suppressive drug interactions.
Cokol M, Weinstein ZB, Yilancioglu K, Tasan M, Doak A, Cansever D, Mutlu B, Li S, Rodriguez-Esteban R, Akhmedov M, Guvenek A, Cokol M, Cetiner S, Giaever G, Iossifov I, Nislow C, Shoichet B, Roth FP. Cokol M, et al. Chem Biol. 2014 Apr 24;21(4):541-551. doi: 10.1016/j.chembiol.2014.02.012. Epub 2014 Apr 3. Chem Biol. 2014. PMID: 24704506 Free PMC article.
Target-independent prediction of drug synergies using only drug lipophilicity.
Yilancioglu K, Weinstein ZB, Meydan C, Akhmetov A, Toprak I, Durmaz A, Iossifov I, Kazan H, Roth FP, Cokol M. Yilancioglu K, et al. Among authors: cokol m. J Chem Inf Model. 2014 Aug 25;54(8):2286-93. doi: 10.1021/ci500276x. Epub 2014 Aug 1. J Chem Inf Model. 2014. PMID: 25026390 Free PMC article.
Modeling the impact of drug interactions on therapeutic selectivity.
Weinstein ZB, Kuru N, Kiriakov S, Palmer AC, Khalil AS, Clemons PA, Zaman MH, Roth FP, Cokol M. Weinstein ZB, et al. Among authors: cokol m. Nat Commun. 2018 Aug 27;9(1):3452. doi: 10.1038/s41467-018-05954-3. Nat Commun. 2018. PMID: 30150706 Free PMC article.
The genetic landscape of a cell.
Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, Alizadeh S, Bahr S, Brost RL, Chen Y, Cokol M, Deshpande R, Li Z, Lin ZY, Liang W, Marback M, Paw J, San Luis BJ, Shuteriqi E, Tong AH, van Dyk N, Wallace IM, Whitney JA, Weirauch MT, Zhong G, Zhu H, Houry WA, Brudno M, Ragibizadeh S, Papp B, Pál C, Roth FP, Giaever G, Nislow C, Troyanskaya OG, Bussey H, Bader GD, Gingras AC, Morris QD, Kim PM, Kaiser CA, Myers CL, Andrews BJ, Boone C. Costanzo M, et al. Among authors: cokol m. Science. 2010 Jan 22;327(5964):425-31. doi: 10.1126/science.1180823. Science. 2010. PMID: 20093466 Free PMC article.
A protein domain-based interactome network for C. elegans early embryogenesis.
Boxem M, Maliga Z, Klitgord N, Li N, Lemmens I, Mana M, de Lichtervelde L, Mul JD, van de Peut D, Devos M, Simonis N, Yildirim MA, Cokol M, Kao HL, de Smet AS, Wang H, Schlaitz AL, Hao T, Milstein S, Fan C, Tipsword M, Drew K, Galli M, Rhrissorrakrai K, Drechsel D, Koller D, Roth FP, Iakoucheva LM, Dunker AK, Bonneau R, Gunsalus KC, Hill DE, Piano F, Tavernier J, van den Heuvel S, Hyman AA, Vidal M. Boxem M, et al. Among authors: cokol m. Cell. 2008 Aug 8;134(3):534-45. doi: 10.1016/j.cell.2008.07.009. Cell. 2008. PMID: 18692475 Free PMC article.
39 results