Sullivan LB - Search Results

1

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

Mullen AR, Wheaton WW, Jin ES, Chen PH, Sullivan LB, Cheng T, Yang Y, Linehan WM, Chandel NS, DeBerardinis RJ. Mullen AR, et al. Among authors: sullivan lb. Nature. 2011 Nov 20;481(7381):385-8. doi: 10.1038/nature10642. Nature. 2011. PMID: 22101431 Free PMC article.

2

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

Mullen AR, Hu Z, Shi X, Jiang L, Boroughs LK, Kovacs Z, Boriack R, Rakheja D, Sullivan LB, Linehan WM, Chandel NS, DeBerardinis RJ. Mullen AR, et al. Among authors: sullivan lb. Cell Rep. 2014 Jun 12;7(5):1679-1690. doi: 10.1016/j.celrep.2014.04.037. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857658 Free PMC article.

3

The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling.

Sullivan LB, Martinez-Garcia E, Nguyen H, Mullen AR, Dufour E, Sudarshan S, Licht JD, Deberardinis RJ, Chandel NS. Sullivan LB, et al. Mol Cell. 2013 Jul 25;51(2):236-48. doi: 10.1016/j.molcel.2013.05.003. Epub 2013 Jun 6. Mol Cell. 2013. PMID: 23747014 Free PMC article.

4

Mitochondrial metabolism in TCA cycle mutant cancer cells.

Sullivan LB, Chandel NS. Sullivan LB, et al. Cell Cycle. 2014;13(3):347-8. doi: 10.4161/cc.27513. Epub 2013 Dec 13. Cell Cycle. 2014. PMID: 24335489 Free PMC article. No abstract available.

5

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis.

Wheaton WW, Weinberg SE, Hamanaka RB, Soberanes S, Sullivan LB, Anso E, Glasauer A, Dufour E, Mutlu GM, Budigner GS, Chandel NS. Wheaton WW, et al. Among authors: sullivan lb. Elife. 2014 May 13;3:e02242. doi: 10.7554/eLife.02242. Elife. 2014. PMID: 24843020 Free PMC article.

6

Mitochondrial reactive oxygen species and cancer.

Sullivan LB, Chandel NS. Sullivan LB, et al. Cancer Metab. 2014 Nov 28;2:17. doi: 10.1186/2049-3002-2-17. eCollection 2014. Cancer Metab. 2014. PMID: 25671107 Free PMC article. Review.

7

Mitochondria and telomeres: the promiscuous roles of TIN2.

Sullivan LB, Santos JH, Chandel NS. Sullivan LB, et al. Mol Cell. 2012 Sep 28;47(6):823-4. doi: 10.1016/j.molcel.2012.09.006. Mol Cell. 2012. PMID: 23020852 Free article.

8

Combined Germline and Mosaic SDHA Mutation Is Associated With a Multicancer Syndrome Including Neuroblastoma, Renal Cancer, and Multifocal GI Tumor.

Cranmer LD, Konnick EQ, Yoshida JR, Jacobson AL, Malik BA, Mogal H, Sullivan LB, Handfrod CL, Pritchard CC, Dubard-Gault ME. Cranmer LD, et al. Among authors: sullivan lb. JCO Precis Oncol. 2024 Jun;8:e2300455. doi: 10.1200/PO.23.00455. JCO Precis Oncol. 2024. PMID: 38885448

9

SRC inhibition enables formation of a growth suppressive MAGI1-PP2A complex in isocitrate dehydrogenase-mutant cholangiocarcinoma.

Luk IS, Bridgwater CM, Yu A, Boila LD, Yáñez-Bartolomé M, Lampano AE, Hulahan TS, Boukhali M, Kathiresan M, Macarulla T, Kenerson HL, Yamamoto N, Sokolov D, Engstrom IA, Sullivan LB, Lampe PD, Cooper JA, Yeung RS, Tian TV, Haas W, Saha SK, Kugel S. Luk IS, et al. Among authors: sullivan lb. Sci Transl Med. 2024 May 15;16(747):eadj7685. doi: 10.1126/scitranslmed.adj7685. Epub 2024 May 15. Sci Transl Med. 2024. PMID: 38748774

10

A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer.

Uo T, Ojo KK, Sprenger CCT, Soriano Epilepsia K, Perera BGK, Damodarasamy M, Sun S, Kim S, Hogan HH, Hulverson MA, Choi R, Whitman GR, Barrett LK, Michaels SA, Xu LH, Sun VL, Arnold SLM, Pang HJ, Nguyen MM, Vigil ABG, Kamat V, Sullivan LB, Sweet IR, Vidadala R, Maly DJ, Van Voorhis WC, Plymate SR. Uo T, et al. Among authors: sullivan lb. Mol Cancer Ther. 2024 Mar 20. doi: 10.1158/1535-7163.MCT-23-0540. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38507737

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