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Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma.
Stefanovic M, Tutusaus A, Martinez-Nieto GA, Bárcena C, de Gregorio E, Moutinho C, Barbero-Camps E, Villanueva A, Colell A, Marí M, García-Ruiz C, Fernandez-Checa JC, Morales A. Stefanovic M, et al. Among authors: morales a. Oncotarget. 2016 Feb 16;7(7):8253-67. doi: 10.18632/oncotarget.6982. Oncotarget. 2016. PMID: 26811497 Free PMC article.
Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent.
Piulats JM, Vidal A, García-Rodríguez FJ, Muñoz C, Nadal M, Moutinho C, Martínez-Iniesta M, Mora J, Figueras A, Guinó E, Padullés L, Aytés À, Molleví DG, Puertas S, Martínez-Fernández C, Castillo W, Juliachs M, Moreno V, Muñoz P, Stefanovic M, Pujana MA, Condom E, Esteller M, Germà JR, Capella G, Farré L, Morales A, Viñals F, García-Del-Muro X, Cerón J, Villanueva A. Piulats JM, et al. Among authors: morales a. Clin Cancer Res. 2018 Aug 1;24(15):3755-3766. doi: 10.1158/1078-0432.CCR-17-1898. Epub 2018 Apr 4. Clin Cancer Res. 2018. PMID: 29618620
Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondria and rat hepatocytes.
García-Ruiz C, Colell A, Morales A, Kaplowitz N, Fernández-Checa JC. García-Ruiz C, et al. Among authors: morales a. Mol Pharmacol. 1995 Nov;48(5):825-34. Mol Pharmacol. 1995. PMID: 7476912
Sphingolipids and cell death.
Morales A, Lee H, Goñi FM, Kolesnick R, Fernandez-Checa JC. Morales A, et al. Apoptosis. 2007 May;12(5):923-39. doi: 10.1007/s10495-007-0721-0. Apoptosis. 2007. PMID: 17294080 Review.
2,160 results