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Frequentist and Bayesian pharmacometric-based approaches to facilitate critically needed new antibiotic development: overcoming lies, damn lies, and statistics.
Ambrose PG, Hammel JP, Bhavnani SM, Rubino CM, Ellis-Grosse EJ, Drusano GL. Ambrose PG, et al. Among authors: rubino cm. Antimicrob Agents Chemother. 2012 Mar;56(3):1466-70. doi: 10.1128/AAC.01743-10. Epub 2011 Dec 12. Antimicrob Agents Chemother. 2012. PMID: 22155834 Free PMC article. Clinical Trial.
Worldwide antimicrobial susceptibility patterns and pharmacodynamic comparisons of gatifloxacin and levofloxacin against Streptococcus pneumoniae: report from the Antimicrobial Resistance Rate Epidemiology Study Team.
Jones RN, Rubino CM, Bhavnani SM, Ambrose PG; Antimicrobial Resistance Rate Epidemiology Study Team Program. Jones RN, et al. Among authors: rubino cm. Antimicrob Agents Chemother. 2003 Jan;47(1):292-6. doi: 10.1128/AAC.47.1.292-296.2003. Antimicrob Agents Chemother. 2003. PMID: 12499204 Free PMC article.
Population pharmacokinetic model for gatifloxacin in pediatric patients.
Rubino CM, Capparelli EV, Bradley JS, Blumer JL, Kearns GL, Reed M, Jacobs RF, Cirincione B, Grasela DM. Rubino CM, et al. Antimicrob Agents Chemother. 2007 Apr;51(4):1246-52. doi: 10.1128/AAC.00685-06. Epub 2007 Jan 12. Antimicrob Agents Chemother. 2007. PMID: 17220409 Free PMC article.
Evaluation of tigecycline penetration into colon wall tissue and epithelial lining fluid using a population pharmacokinetic model and Monte Carlo simulation.
Rubino CM, Ma L, Bhavnani SM, Korth-Bradley J, Speth J, Ellis-Grosse E, Rodvold KR, Ambrose PG, Drusano GL. Rubino CM, et al. Antimicrob Agents Chemother. 2007 Nov;51(11):4085-9. doi: 10.1128/AAC.00065-07. Epub 2007 Sep 10. Antimicrob Agents Chemother. 2007. PMID: 17846139 Free PMC article. Clinical Trial.
85 results