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Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved.
Gupta A, Akki A, Wang Y, Leppo MK, Chacko VP, Foster DB, Caceres V, Shi S, Kirk JA, Su J, Lai S, Paolocci N, Steenbergen C, Gerstenblith G, Weiss RG. Gupta A, et al. Among authors: foster db. J Clin Invest. 2012 Jan;122(1):291-302. doi: 10.1172/JCI57426. Epub 2011 Dec 27. J Clin Invest. 2012. PMID: 22201686 Free PMC article.
Global knockout of ROMK potassium channel worsens cardiac ischemia-reperfusion injury but cardiomyocyte-specific knockout does not: Implications for the identity of mitoKATP.
Papanicolaou KN, Ashok D, Liu T, Bauer TM, Sun J, Li Z, da Costa E, D'Orleans CC, Nathan S, Lefer DJ, Murphy E, Paolocci N, Foster DB, O'Rourke B. Papanicolaou KN, et al. Among authors: foster db. J Mol Cell Cardiol. 2020 Feb;139:176-189. doi: 10.1016/j.yjmcc.2020.01.010. Epub 2020 Jan 29. J Mol Cell Cardiol. 2020. PMID: 32004507 Free PMC article.
Phosphorylation of protein kinase C sites Ser42/44 decreases Ca(2+)-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes.
Wijnker PJ, Sequeira V, Witjas-Paalberends ER, Foster DB, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Among authors: foster db. Arch Biochem Biophys. 2014 Jul 15;554:11-21. doi: 10.1016/j.abb.2014.04.017. Epub 2014 May 9. Arch Biochem Biophys. 2014. PMID: 24814372 Free PMC article.
Cardiac troponin I Pro82Ser variant induces diastolic dysfunction, blunts β-adrenergic response, and impairs myofilament cooperativity.
Ramirez-Correa GA, Frazier AH, Zhu G, Zhang P, Rappold T, Kooij V, Bedja D, Snyder GA, Lugo-Fagundo NS, Hariharan R, Li Y, Shen X, Gao WD, Cingolani OH, Takimoto E, Foster DB, Murphy AM. Ramirez-Correa GA, et al. Among authors: foster db. J Appl Physiol (1985). 2015 Jan 15;118(2):212-23. doi: 10.1152/japplphysiol.00463.2014. Epub 2014 Oct 16. J Appl Physiol (1985). 2015. PMID: 25324519 Free PMC article.
81 results