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An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice.
J Clin Invest. 2012 Feb;122(2):553-7. doi: 10.1172/JCI59309. Epub 2012 Jan 3.
J Clin Invest. 2012.
PMID: 22214849
Free PMC article.
Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors.
Tikoo A, Roh V, Montgomery KG, Ivetac I, Waring P, Pelzer R, Hare L, Shackleton M, Humbert P, Phillips WA.
Tikoo A, et al. Among authors: ivetac i.
PLoS One. 2012;7(5):e36924. doi: 10.1371/journal.pone.0036924. Epub 2012 May 30.
PLoS One. 2012.
PMID: 22666336
Free PMC article.
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Assessing the subcellular distribution of oncogenic phosphoinositide 3-kinase using microinjection into live cells.
Layton MJ, Rynkiewicz NK, Ivetac I, Horan KA, Mitchell CA, Phillips WA.
Layton MJ, et al. Among authors: ivetac i.
Biosci Rep. 2014 Apr 1;34(2):e00104. doi: 10.1042/BSR20130133. Print 2014 Apr 1.
Biosci Rep. 2014.
PMID: 27919038
Free PMC article.
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The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.
Ooms LM, Fedele CG, Astle MV, Ivetac I, Cheung V, Pearson RB, Layton MJ, Forrai A, Nandurkar HH, Mitchell CA.
Ooms LM, et al. Among authors: ivetac i.
Mol Biol Cell. 2006 Feb;17(2):607-22. doi: 10.1091/mbc.e05-05-0469. Epub 2005 Nov 9.
Mol Biol Cell. 2006.
PMID: 16280363
Free PMC article.
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Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.
Ivetac I, Gurung R, Hakim S, Horan KA, Sheffield DA, Binge LC, Majerus PW, Tiganis T, Mitchell CA.
Ivetac I, et al.
EMBO Rep. 2009 May;10(5):487-93. doi: 10.1038/embor.2009.28. Epub 2009 Mar 27.
EMBO Rep. 2009.
PMID: 19325558
Free PMC article.
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The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane.
Ivetac I, Munday AD, Kisseleva MV, Zhang XM, Luff S, Tiganis T, Whisstock JC, Rowe T, Majerus PW, Mitchell CA.
Ivetac I, et al.
Mol Biol Cell. 2005 May;16(5):2218-33. doi: 10.1091/mbc.e04-09-0799. Epub 2005 Feb 16.
Mol Biol Cell. 2005.
PMID: 15716355
Free PMC article.
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Role of ATP during the initiation of microvascularization: acceleration of an autocrine sensing mechanism facilitating chemotaxis by inorganic polyphosphate.
Müller WEG, Ackermann M, Tolba E, Neufurth M, Ivetac I, Kokkinopoulou M, Schröder HC, Wang X.
Müller WEG, et al. Among authors: ivetac i.
Biochem J. 2018 Oct 31;475(20):3255-3273. doi: 10.1042/BCJ20180535.
Biochem J. 2018.
PMID: 30242064
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