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The interaction of PKN3 with RhoC promotes malignant growth.
Mol Oncol. 2012 Jun;6(3):284-98. doi: 10.1016/j.molonc.2011.12.001. Epub 2011 Dec 28.
Mol Oncol. 2012.
PMID: 22217540
Free PMC article.
p120 catenin is a key effector of a Ras-PKCɛ oncogenic signaling axis.
Dann SG, Golas J, Miranda M, Shi C, Wu J, Jin G, Rosfjord E, Upeslacis E, Klippel A.
Dann SG, et al. Among authors: upeslacis e.
Oncogene. 2014 Mar 13;33(11):1385-94. doi: 10.1038/onc.2013.91. Epub 2013 Apr 1.
Oncogene. 2014.
PMID: 23542175
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2-Aryl-4,5,6,7-tetrahydro-1,3-benzothiazol-7-ols as a class of antitumor agents selectively active in securin(-/-) cells.
Zhang N, Ayral-Kaloustian S, Niu C, Nguyen T, Upeslacis E, Mansour TS, Ragunathan S, Rosfjord E.
Zhang N, et al. Among authors: upeslacis e.
Bioorg Med Chem Lett. 2010 Jul 1;20(13):3903-5. doi: 10.1016/j.bmcl.2010.05.021. Epub 2010 May 12.
Bioorg Med Chem Lett. 2010.
PMID: 20627558
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Anti-tumor immunity influences cancer cell reliance upon ATG7.
Arensman MD, Yang XS, Zhong W, Bisulco S, Upeslacis E, Rosfjord EC, Deng S, Abraham RT, Eng CH.
Arensman MD, et al. Among authors: upeslacis e.
Oncoimmunology. 2020 Aug 23;9(1):1800162. doi: 10.1080/2162402X.2020.1800162.
Oncoimmunology. 2020.
PMID: 32923161
Free PMC article.
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A Novel GUCY2C-CD3 T-Cell Engaging Bispecific Construct (PF-07062119) for the Treatment of Gastrointestinal Cancers.
Mathur D, Root AR, Bugaj-Gaweda B, Bisulco S, Tan X, Fang W, Kearney JC, Lucas J, Guffroy M, Golas J, Rohde CM, Stevens C, Kamperschroer C, Kelleher K, Lawrence-Henderson RF, Upeslacis E, Yao J, Narula J, LaVallie ER, Fernandez DR, Buetow BS, Rosfjord E, Bloom L, King LE, Tchistiakova L, Nguyen A, Sapra P.
Mathur D, et al. Among authors: upeslacis e.
Clin Cancer Res. 2020 May 1;26(9):2188-2202. doi: 10.1158/1078-0432.CCR-19-3275. Epub 2020 Jan 29.
Clin Cancer Res. 2020.
PMID: 31996389
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Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions.
Damelin M, Bankovich A, Park A, Aguilar J, Anderson W, Santaguida M, Aujay M, Fong S, Khandke K, Pulito V, Ernstoff E, Escarpe P, Bernstein J, Pysz M, Zhong W, Upeslacis E, Lucas J, Lucas J, Nichols T, Loving K, Foord O, Hampl J, Stull R, Barletta F, Falahatpisheh H, Sapra P, Gerber HP, Dylla SJ.
Damelin M, et al. Among authors: upeslacis e.
Clin Cancer Res. 2015 Sep 15;21(18):4165-73. doi: 10.1158/1078-0432.CCR-15-0695. Epub 2015 May 26.
Clin Cancer Res. 2015.
PMID: 26015513
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4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6,7-dialkoxyquinazoline inhibitors.
Wissner A, Berger DM, Boschelli DH, Floyd MB Jr, Greenberger LM, Gruber BC, Johnson BD, Mamuya N, Nilakantan R, Reich MF, Shen R, Tsou HR, Upeslacis E, Wang YF, Wu B, Ye F, Zhang N.
Wissner A, et al. Among authors: upeslacis e.
J Med Chem. 2000 Aug 24;43(17):3244-56. doi: 10.1021/jm000206a.
J Med Chem. 2000.
PMID: 10966743
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