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AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model.
Raake PW, Schlegel P, Ksienzyk J, Reinkober J, Barthelmes J, Schinkel S, Pleger S, Mier W, Haberkorn U, Koch WJ, Katus HA, Most P, Müller OJ. Raake PW, et al. Among authors: pleger s. Eur Heart J. 2013 May;34(19):1437-47. doi: 10.1093/eurheartj/ehr447. Epub 2012 Jan 19. Eur Heart J. 2013. PMID: 22261894 Free PMC article.
S100A1 gene therapy in small and large animals.
Most P, Raake P, Weber C, Katus HA, Pleger ST. Most P, et al. Methods Mol Biol. 2013;963:407-20. doi: 10.1007/978-1-62703-230-8_25. Methods Mol Biol. 2013. PMID: 23296625
Heart failure gene therapy: the path to clinical practice.
Pleger ST, Brinks H, Ritterhoff J, Raake P, Koch WJ, Katus HA, Most P. Pleger ST, et al. Circ Res. 2013 Aug 30;113(6):792-809. doi: 10.1161/CIRCRESAHA.113.300269. Circ Res. 2013. PMID: 23989720 Review.
Comprehensive cardiac phenotyping in large animals: comparison of pressure-volume analysis and cardiac magnetic resonance imaging in pig post-myocardial infarction systolic heart failure.
Raake PWJ, Barthelmes J, Krautz B, Buss S, Huditz R, Schlegel P, Weber C, Stangassinger M, Haberkorn U, Katus HA, Most P, Pleger ST. Raake PWJ, et al. Among authors: pleger st. Int J Cardiovasc Imaging. 2019 Sep;35(9):1691-1699. doi: 10.1007/s10554-019-01610-z. Epub 2019 May 5. Int J Cardiovasc Imaging. 2019. PMID: 31056718
S100A1 gene transfer in myocardium.
Pleger ST, Most P, Heidt B, Voelkers M, Hata JA, Katus HA, Remppis A, Koch WJ. Pleger ST, et al. Eur J Med Res. 2006 Oct 27;11(10):418-22. Eur J Med Res. 2006. PMID: 17107875
Hope for a broken heart?
Most P, Eicher C, Völkers M, Pleger ST, Katus HA. Most P, et al. Trends Biotechnol. 2004 Oct;22(10):487-9. doi: 10.1016/j.tibtech.2004.08.004. Trends Biotechnol. 2004. PMID: 15450736
S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction.
Pleger ST, Remppis A, Heidt B, Völkers M, Chuprun JK, Kuhn M, Zhou RH, Gao E, Szabo G, Weichenhan D, Müller OJ, Eckhart AD, Katus HA, Koch WJ, Most P. Pleger ST, et al. Mol Ther. 2005 Dec;12(6):1120-9. doi: 10.1016/j.ymthe.2005.08.002. Epub 2005 Sep 15. Mol Ther. 2005. PMID: 16168714 Free article.
89 results