Wang Y - Search Results

1

Effect of hepatic impairment on the pharmacokinetics of pasireotide (SOM230): results from a multicenter phase I study.

Horsmans Y, Hu K, Ruffin M, Wang Y, Song D, Bouillaud E, Wang Y, Mazur D, Botha FP, Heuman DM. Horsmans Y, et al. Among authors: wang y. J Clin Pharmacol. 2012 Apr;52(4):552-8. doi: 10.1177/0091270011400072. Epub 2012 Jan 26. J Clin Pharmacol. 2012. PMID: 22282526 Clinical Trial.

2

Pasireotide (SOM230), a novel multireceptor-targeted somatostatin analogue, is well tolerated when administered as a continuous 7-day subcutaneous infusion in healthy male volunteers.

Petersenn S, Unger N, Hu K, Weisshaar B, Zhang Y, Bouillaud E, Reséndiz KH, Wang Y, Mann K. Petersenn S, et al. Among authors: wang y. J Clin Pharmacol. 2012 Jul;52(7):1017-27. doi: 10.1177/0091270011408727. Epub 2011 Jun 14. J Clin Pharmacol. 2012. PMID: 21673137 Clinical Trial.

3

Tolerability and dose proportional pharmacokinetics of pasireotide administered as a single dose or two divided doses in healthy male volunteers: a single-center, open-label, ascending-dose study.

Petersenn S, Hu K, Maldonado M, Zhang Y, Lasher J, Bouillaud E, Wang Y, Mann K, Unger N. Petersenn S, et al. Among authors: wang y. Clin Ther. 2012 Mar;34(3):677-88. doi: 10.1016/j.clinthera.2012.01.015. Epub 2012 Feb 24. Clin Ther. 2012. PMID: 22364824 Clinical Trial.

4

Safety, tolerability, and pharmacokinetics of a single dose of pasireotide long-acting release in healthy volunteers: a single-center Phase I study.

Dietrich H, Hu K, Ruffin M, Song D, Bouillaud E, Wang Y, Hasskarl J. Dietrich H, et al. Among authors: wang y. Eur J Endocrinol. 2012 May;166(5):821-8. doi: 10.1530/EJE-11-0773. Epub 2012 Mar 1. Eur J Endocrinol. 2012. PMID: 22383336 Clinical Trial.

5

Multiple once-daily subcutaneous doses of pasireotide were well tolerated in healthy male volunteers: a randomized, double-blind, placebo-controlled, cross-over, Phase I study.

Beglinger C, Hu K, Wang Y, Bouillaud E, Darstein C, Wang Y, Mohideen P. Beglinger C, et al. Among authors: wang y. Endocrine. 2012 Oct;42(2):366-74. doi: 10.1007/s12020-012-9668-1. Epub 2012 Apr 21. Endocrine. 2012. PMID: 22527887 Clinical Trial.

6

A first-in-man study to evaluate the safety, tolerability, and pharmacokinetics of pasireotide (SOM230), a multireceptor-targeted somatostatin analog, in healthy volunteers.

Golor G, Hu K, Ruffin M, Buchelt A, Bouillaud E, Wang Y, Maldonado M. Golor G, et al. Among authors: wang y. Drug Des Devel Ther. 2012;6:71-9. doi: 10.2147/DDDT.S29125. Epub 2012 Apr 19. Drug Des Devel Ther. 2012. PMID: 22573933 Free PMC article. Clinical Trial.

7

An open-label dose-escalation study of once-daily and twice-daily pasireotide in healthy volunteers: safety, tolerability, and effects on glucose, insulin, and glucagon levels.

Shenouda M, Maldonado M, Wang Y, Bouillaud E, Hudson M, Nesheiwat D, Hu K. Shenouda M, et al. Among authors: wang y. Am J Ther. 2014 May-Jun;21(3):164-73. doi: 10.1097/MJT.0b013e31824c3eb4. Am J Ther. 2014. PMID: 22713526 Clinical Trial.

8

Dose- and time-dependent pharmacokinetics of midostaurin in patients with diabetes mellitus.

Wang Y, Yin OQ, Graf P, Kisicki JC, Schran H. Wang Y, et al. J Clin Pharmacol. 2008 Jun;48(6):763-75. doi: 10.1177/0091270008318006. J Clin Pharmacol. 2008. PMID: 18508951 Clinical Trial.

9

Pharmacokinetic-pharmacodynamic comparison of a novel multiligand somatostatin analog, SOM230, with octreotide in patients with acromegaly.

Ma P, Wang Y, van der Hoek J, Nedelman J, Schran H, Tran LL, Lamberts SW. Ma P, et al. Among authors: wang y. Clin Pharmacol Ther. 2005 Jul;78(1):69-80. doi: 10.1016/j.clpt.2005.04.003. Clin Pharmacol Ther. 2005. PMID: 16003295 Clinical Trial.

10

Population Pharmacokinetics of Nusinersen in the Cerebral Spinal Fluid and Plasma of Pediatric Patients With Spinal Muscular Atrophy Following Intrathecal Administrations.

Luu KT, Norris DA, Gunawan R, Henry S, Geary R, Wang Y. Luu KT, et al. Among authors: wang y. J Clin Pharmacol. 2017 Aug;57(8):1031-1041. doi: 10.1002/jcph.884. Epub 2017 Mar 29. J Clin Pharmacol. 2017. PMID: 28369979

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