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Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib).
Mol Cancer Ther. 2017 Nov;16(11):2351-2363. doi: 10.1158/1535-7163.MCT-17-0456. Epub 2017 Sep 22.
Mol Cancer Ther. 2017.
PMID: 28939558
Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin.
Hall JC, Marlow LA, Mathias AC, Dawson LK, Durham WF, Meshaw KA, Mullin RJ, Synnott AJ, Small DL, Krishna M, von Hoff D, Schüler J, Hart SN, Couch FJ, Colon-Otero G, Copland JA.
Hall JC, et al. Among authors: meshaw ka.
J Transl Med. 2016 May 10;14(1):129. doi: 10.1186/s12967-016-0875-z.
J Transl Med. 2016.
PMID: 27165126
Free PMC article.
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Systematic repurposing screening in xenograft models identifies approved drugs with novel anti-cancer activity.
Roix JJ, Harrison SD, Rainbolt EA, Meshaw KR, McMurry AS, Cheung P, Saha S.
Roix JJ, et al. Among authors: meshaw kr.
PLoS One. 2014 Aug 5;9(8):e101708. doi: 10.1371/journal.pone.0101708. eCollection 2014.
PLoS One. 2014.
PMID: 25093583
Free PMC article.
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Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib.
Kirane A, Toombs JE, Larsen JE, Ostapoff KT, Meshaw KR, Zaknoen S, Brekken RA, Burrows FJ.
Kirane A, et al. Among authors: meshaw kr.
Carcinogenesis. 2012 Sep;33(9):1639-46. doi: 10.1093/carcin/bgs195. Epub 2012 Jun 7.
Carcinogenesis. 2012.
PMID: 22678114
Free PMC article.
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Immunotoxicologic effects of cyclosporine on tumor progression in models of squamous cell carcinoma and B-cell lymphoma in C3H mice.
Rafferty P, Egenolf D, Brosnan K, Makropoulos D, Jordan J, Meshaw K, Walker M, Volk A, Bugelski PJ.
Rafferty P, et al. Among authors: meshaw k.
J Immunotoxicol. 2012 Jan-Mar;9(1):43-55. doi: 10.3109/1547691X.2011.614646.
J Immunotoxicol. 2012.
PMID: 22299716
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Identification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen.
Gelman MS, Ye XK, Stull R, Suhy D, Jin L, Ng D, Than B, Ji M, Pan A, Perez P, Sun Y, Yeung P, Garcia LM, Harte R, Lu Y, Lamar E, Tavassoli R, Kennedy S, Osborn S, Chin DJ, Meshaw K, Holzmayer TA, Axenovich SA, Abo A.
Gelman MS, et al. Among authors: meshaw k.
Oncogene. 2004 Oct 21;23(49):8158-70. doi: 10.1038/sj.onc.1208054.
Oncogene. 2004.
PMID: 15361835
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Alpha-lactalbumin as a modulator of mammary cellular activity.
Alston-Mills B, Hepler CD, Sternhagen L, Allen JC, Meshaw KA.
Alston-Mills B, et al. Among authors: meshaw ka.
In Vitro Cell Dev Biol Anim. 1998 Nov-Dec;34(10):747-50. doi: 10.1007/s11626-998-0026-9.
In Vitro Cell Dev Biol Anim. 1998.
PMID: 9870521
No abstract available.
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