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Page 1
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.
Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, Nussenzweig A, Hager GL, Nussenzweig MC, Casellas R. Hakim O, et al. Nature. 2012 Feb 7;484(7392):69-74. doi: 10.1038/nature10909. Nature. 2012. PMID: 22314321 Free PMC article.
3D shortcuts to gene regulation.
Hakim O, Sung MH, Hager GL. Hakim O, et al. Curr Opin Cell Biol. 2010 Jun;22(3):305-13. doi: 10.1016/j.ceb.2010.04.005. Epub 2010 May 11. Curr Opin Cell Biol. 2010. PMID: 20466532 Free PMC article. Review.
Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation.
Kovalchuk AL, Ansarah-Sobrinho C, Hakim O, Resch W, Tolarová H, Dubois W, Yamane A, Takizawa M, Klein I, Hager GL, Morse HC 3rd, Potter M, Nussenzweig MC, Casellas R. Kovalchuk AL, et al. Among authors: hakim o. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10972-7. doi: 10.1073/pnas.1200106109. Epub 2012 Jun 18. Proc Natl Acad Sci U S A. 2012. PMID: 22711821 Free PMC article.
Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.
Kieffer-Kwon KR, Tang Z, Mathe E, Qian J, Sung MH, Li G, Resch W, Baek S, Pruett N, Grøntved L, Vian L, Nelson S, Zare H, Hakim O, Reyon D, Yamane A, Nakahashi H, Kovalchuk AL, Zou J, Joung JK, Sartorelli V, Wei CL, Ruan X, Hager GL, Ruan Y, Casellas R. Kieffer-Kwon KR, et al. Among authors: hakim o. Cell. 2013 Dec 19;155(7):1507-20. doi: 10.1016/j.cell.2013.11.039. Cell. 2013. PMID: 24360274 Free PMC article.
B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.
Qian J, Wang Q, Dose M, Pruett N, Kieffer-Kwon KR, Resch W, Liang G, Tang Z, Mathé E, Benner C, Dubois W, Nelson S, Vian L, Oliveira TY, Jankovic M, Hakim O, Gazumyan A, Pavri R, Awasthi P, Song B, Liu G, Chen L, Zhu S, Feigenbaum L, Staudt L, Murre C, Ruan Y, Robbiani DF, Pan-Hammarström Q, Nussenzweig MC, Casellas R. Qian J, et al. Among authors: hakim o. Cell. 2014 Dec 18;159(7):1524-37. doi: 10.1016/j.cell.2014.11.013. Epub 2014 Dec 4. Cell. 2014. PMID: 25483777 Free PMC article.
Epigenetic targeting of activation-induced cytidine deaminase.
Wang Q, Oliveira T, Jankovic M, Silva IT, Hakim O, Yao K, Gazumyan A, Mayer CT, Pavri R, Casellas R, Nussenzweig MC, Robbiani DF. Wang Q, et al. Among authors: hakim o. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18667-72. doi: 10.1073/pnas.1420575111. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512519 Free PMC article.
Cajal bodies are linked to genome conformation.
Wang Q, Sawyer IA, Sung MH, Sturgill D, Shevtsov SP, Pegoraro G, Hakim O, Baek S, Hager GL, Dundr M. Wang Q, et al. Among authors: hakim o. Nat Commun. 2016 Mar 21;7:10966. doi: 10.1038/ncomms10966. Nat Commun. 2016. PMID: 26997247 Free PMC article.
69 results