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Saposins utilize two strategies for lipid transfer and CD1 antigen presentation.
León L, Tatituri RV, Grenha R, Sun Y, Barral DC, Minnaard AJ, Bhowruth V, Veerapen N, Besra GS, Kasmar A, Peng W, Moody DB, Grabowski GA, Brenner MB. León L, et al. Among authors: tatituri rv. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4357-64. doi: 10.1073/pnas.1200764109. Epub 2012 Feb 13. Proc Natl Acad Sci U S A. 2012. PMID: 22331868 Free PMC article.
Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.
Tatituri RV, Watts GF, Bhowruth V, Barton N, Rothchild A, Hsu FF, Almeida CF, Cox LR, Eggeling L, Cardell S, Rossjohn J, Godfrey DI, Behar SM, Besra GS, Brenner MB, Brigl M. Tatituri RV, et al. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1827-32. doi: 10.1073/pnas.1220601110. Epub 2013 Jan 10. Proc Natl Acad Sci U S A. 2013. PMID: 23307809 Free PMC article.
Human autoreactive T cells recognize CD1b and phospholipids.
Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB. Van Rhijn I, et al. Among authors: tatituri rv. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):380-5. doi: 10.1073/pnas.1520947112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2016. PMID: 26621732 Free PMC article.
Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells.
Wolf BJ, Tatituri RV, Almeida CF, Le Nours J, Bhowruth V, Johnson D, Uldrich AP, Hsu FF, Brigl M, Besra GS, Rossjohn J, Godfrey DI, Brenner MB. Wolf BJ, et al. Among authors: tatituri rv. J Immunol. 2015 Sep 15;195(6):2540-51. doi: 10.4049/jimmunol.1501019. Epub 2015 Aug 7. J Immunol. 2015. PMID: 26254340 Free PMC article.
Identification of an alpha(1-->6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosis.
Mishra AK, Alderwick LJ, Rittmann D, Tatituri RV, Nigou J, Gilleron M, Eggeling L, Besra GS. Mishra AK, et al. Among authors: tatituri rv. Mol Microbiol. 2007 Sep;65(6):1503-17. doi: 10.1111/j.1365-2958.2007.05884.x. Epub 2007 Aug 21. Mol Microbiol. 2007. PMID: 17714444 Free PMC article.
18 results