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Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.
Lee SH, DeCandia TR, Ripke S, Yang J; Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ); International Schizophrenia Consortium (ISC); Molecular Genetics of Schizophrenia Collaboration (MGS); Sullivan PF, Goddard ME, Keller MC, Visscher PM, Wray NR. Lee SH, et al. Among authors: keller mc. Nat Genet. 2012 Feb 19;44(3):247-50. doi: 10.1038/ng.1108. Nat Genet. 2012. PMID: 22344220 Free PMC article.
Runs of homozygosity implicate autozygosity as a schizophrenia risk factor.
Keller MC, Simonson MA, Ripke S, Neale BM, Gejman PV, Howrigan DP, Lee SH, Lencz T, Levinson DF, Sullivan PF; Schizophrenia Psychiatric Genome-Wide Association Study Consortium. Keller MC, et al. PLoS Genet. 2012;8(4):e1002656. doi: 10.1371/journal.pgen.1002656. Epub 2012 Apr 12. PLoS Genet. 2012. PMID: 22511889 Free PMC article.
Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects.
Howe LJ, Nivard MG, Morris TT, Hansen AF, Rasheed H, Cho Y, Chittoor G, Ahlskog R, Lind PA, Palviainen T, van der Zee MD, Cheesman R, Mangino M, Wang Y, Li S, Klaric L, Ratliff SM, Bielak LF, Nygaard M, Giannelis A, Willoughby EA, Reynolds CA, Balbona JV, Andreassen OA, Ask H, Baras A, Bauer CR, Boomsma DI, Campbell A, Campbell H, Chen Z, Christofidou P, Corfield E, Dahm CC, Dokuru DR, Evans LM, de Geus EJC, Giddaluru S, Gordon SD, Harden KP, Hill WD, Hughes A, Kerr SM, Kim Y, Kweon H, Latvala A, Lawlor DA, Li L, Lin K, Magnus P, Magnusson PKE, Mallard TT, Martikainen P, Mills MC, Njølstad PR, Overton JD, Pedersen NL, Porteous DJ, Reid J, Silventoinen K, Southey MC, Stoltenberg C, Tucker-Drob EM, Wright MJ; Social Science Genetic Association Consortium; Within Family Consortium; Hewitt JK, Keller MC, Stallings MC, Lee JJ, Christensen K, Kardia SLR, Peyser PA, Smith JA, Wilson JF, Hopper JL, Hägg S, Spector TD, Pingault JB, Plomin R, Havdahl A, Bartels M, Martin NG, Oskarsson S, Justice AE, Millwood IY, Hveem K, Naess Ø, Willer CJ, Åsvold BO, Koellinger PD, Kaprio J, Medland SE, Walters RG, Benjamin DJ, Turley P, Evans DM, Davey Smith G, Hayward C, Brumpton B, Hemani G, Davi… See abstract for full author list ➔ Howe LJ, et al. Among authors: keller mc. Nat Genet. 2022 May;54(5):581-592. doi: 10.1038/s41588-022-01062-7. Epub 2022 May 9. Nat Genet. 2022. PMID: 35534559 Free PMC article.
159 results