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Page 1
Might the observed α(2A)-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations?
Diamanti E, Del Bello F, Carbonara G, Carrieri A, Fracchiolla G, Giannella M, Mammoli V, Piergentili A, Pohjanoksa K, Quaglia W, Scheinin M, Pigini M. Diamanti E, et al. Among authors: mammoli v. Bioorg Med Chem. 2012 Mar 15;20(6):2082-90. doi: 10.1016/j.bmc.2012.01.035. Epub 2012 Jan 31. Bioorg Med Chem. 2012. PMID: 22341244
Low Doses of Allyphenyline and Cyclomethyline, Effective against Morphine Dependence, Elicit an Antidepressant-like Effect.
Del Bello F, Diamanti E, Giannella M, Mammoli V, Marchioro C, Mattioli L, Titomanlio F, Piergentili A, Quaglia W, Benedetti G, Varrone M, Pigini M. Del Bello F, et al. Among authors: mammoli v. ACS Med Chem Lett. 2012 Jun 8;3(7):535-9. doi: 10.1021/ml300064v. eCollection 2012 Jul 12. ACS Med Chem Lett. 2012. PMID: 24900506 Free PMC article.
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation.
Del Bello F, Bargelli V, Cifani C, Gratteri P, Bazzicalupi C, Diamanti E, Giannella M, Mammoli V, Matucci R, Micioni Di Bonaventura MV, Piergentili A, Quaglia W, Pigini M. Del Bello F, et al. Among authors: mammoli v. ACS Med Chem Lett. 2015 Apr 3;6(5):496-501. doi: 10.1021/acsmedchemlett.5b00115. eCollection 2015 May 14. ACS Med Chem Lett. 2015. PMID: 26005521 Free PMC article.
Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring.
Bonifazi A, Del Bello F, Mammoli V, Piergentili A, Petrelli R, Cimarelli C, Pellei M, Schepmann D, Wünsch B, Barocelli E, Bertoni S, Flammini L, Amantini C, Nabissi M, Santoni G, Vistoli G, Quaglia W. Bonifazi A, et al. Among authors: mammoli v. J Med Chem. 2015 Nov 12;58(21):8601-15. doi: 10.1021/acs.jmedchem.5b01214. Epub 2015 Oct 14. J Med Chem. 2015. PMID: 26430967
Biological profile and bioavailability of imidazoline compounds on morphine tolerance modulation.
Caprioli G, Mammoli V, Ricciutelli M, Sagratini G, Ubaldi M, Domi E, Mennuni L, Sabatini C, Galimberti C, Ferrari F, Milia C, Comi E, Lanza M, Giannella M, Pigini M, Del Bello F. Caprioli G, et al. Among authors: mammoli v. Eur J Pharmacol. 2015 Dec 15;769:219-24. doi: 10.1016/j.ejphar.2015.11.021. Epub 2015 Nov 24. Eur J Pharmacol. 2015. PMID: 26593429 Free article.
A Novel Class of Dopamine D4 Receptor Ligands Bearing an Imidazoline Nucleus.
Mammoli V, Bonifazi A, Dal Ben D, Giannella M, Giorgioni G, Piergentili A, Pigini M, Quaglia W, Thomas A, Newman AH, Ferré S, Sanchez-Soto M, Keck TM, Del Bello F. Mammoli V, et al. ChemMedChem. 2016 Aug 19;11(16):1819-28. doi: 10.1002/cmdc.201600022. Epub 2016 Mar 15. ChemMedChem. 2016. PMID: 26990230 Free PMC article.
The Versatile 2-Substituted Imidazoline Nucleus as a Structural Motif of Ligands Directed to the Serotonin 5-HT1A Receptor.
Del Bello F, Cilia A, Carrieri A, Fasano DC, Ghelardini C, Di Cesare Mannelli L, Micheli L, Santini C, Diamanti E, Giannella M, Giorgioni G, Mammoli V, Paoletti CD, Petrelli R, Piergentili A, Quaglia W, Pigini M. Del Bello F, et al. Among authors: mammoli v. ChemMedChem. 2016 Oct 19;11(20):2287-2298. doi: 10.1002/cmdc.201600383. Epub 2016 Sep 30. ChemMedChem. 2016. PMID: 27690321
Combined Interactions with I1-, I2-Imidazoline Binding Sites and α2-Adrenoceptors To Manage Opioid Addiction.
Giusepponi ME, Cifani C, Micioni Di Bonaventura MV, Mattioli L, Hudson A, Diamanti E, Del Bello F, Giannella M, Mammoli V, Paoletti CD, Piergentili A, Pigini M, Quaglia W. Giusepponi ME, et al. Among authors: mammoli v. ACS Med Chem Lett. 2016 Sep 8;7(10):956-961. doi: 10.1021/acsmedchemlett.6b00290. eCollection 2016 Oct 13. ACS Med Chem Lett. 2016. PMID: 27774136 Free PMC article.
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