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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome.
Carvajal-Vergara X, Sevilla A, D'Souza SL, Ang YS, Schaniel C, Lee DF, Yang L, Kaplan AD, Adler ED, Rozov R, Ge Y, Cohen N, Edelmann LJ, Chang B, Waghray A, Su J, Pardo S, Lichtenbelt KD, Tartaglia M, Gelb BD, Lemischka IR. Carvajal-Vergara X, et al. Among authors: sevilla a. Nature. 2010 Jun 10;465(7299):808-12. doi: 10.1038/nature09005. Nature. 2010. PMID: 20535210 Free PMC article.
Prdm16 is a physiologic regulator of hematopoietic stem cells.
Aguilo F, Avagyan S, Labar A, Sevilla A, Lee DF, Kumar P, Lemischka IR, Zhou BY, Snoeck HW. Aguilo F, et al. Among authors: sevilla a. Blood. 2011 May 12;117(19):5057-66. doi: 10.1182/blood-2010-08-300145. Epub 2011 Feb 22. Blood. 2011. PMID: 21343612 Free PMC article.
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling.
Lee DF, Su J, Ang YS, Carvajal-Vergara X, Mulero-Navarro S, Pereira CF, Gingold J, Wang HL, Zhao R, Sevilla A, Darr H, Williamson AJ, Chang B, Niu X, Aguilo F, Flores ER, Sher YP, Hung MC, Whetton AD, Gelb BD, Moore KA, Snoeck HW, Ma'ayan A, Schaniel C, Lemischka IR. Lee DF, et al. Among authors: sevilla a. Cell Stem Cell. 2012 Aug 3;11(2):179-94. doi: 10.1016/j.stem.2012.05.020. Cell Stem Cell. 2012. PMID: 22862944 Free PMC article.
Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity.
MacArthur BD, Sevilla A, Lenz M, Müller FJ, Schuldt BM, Schuppert AA, Ridden SJ, Stumpf PS, Fidalgo M, Ma'ayan A, Wang J, Lemischka IR. MacArthur BD, et al. Among authors: sevilla a. Nat Cell Biol. 2012 Nov;14(11):1139-47. doi: 10.1038/ncb2603. Epub 2012 Oct 28. Nat Cell Biol. 2012. PMID: 23103910 Free PMC article.
Patterning pluripotency in embryonic stem cells.
Zhang YS, Sevilla A, Wan LQ, Lemischka IR, Vunjak-Novakovic G. Zhang YS, et al. Among authors: sevilla a. Stem Cells. 2013 Sep;31(9):1806-15. doi: 10.1002/stem.1468. Stem Cells. 2013. PMID: 23843329 Free PMC article.
Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells.
Paull D, Sevilla A, Zhou H, Hahn AK, Kim H, Napolitano C, Tsankov A, Shang L, Krumholz K, Jagadeesan P, Woodard CM, Sun B, Vilboux T, Zimmer M, Forero E, Moroziewicz DN, Martinez H, Malicdan MC, Weiss KA, Vensand LB, Dusenberry CR, Polus H, Sy KT, Kahler DJ, Gahl WA, Solomon SL, Chang S, Meissner A, Eggan K, Noggle SA. Paull D, et al. Among authors: sevilla a. Nat Methods. 2015 Sep;12(9):885-92. doi: 10.1038/nmeth.3507. Epub 2015 Aug 3. Nat Methods. 2015. PMID: 26237226
Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia.
Mulero-Navarro S, Sevilla A, Roman AC, Lee DF, D'Souza SL, Pardo S, Riess I, Su J, Cohen N, Schaniel C, Rodriguez NA, Baccarini A, Brown BD, Cavé H, Caye A, Strullu M, Yalcin S, Park CY, Dhandapany PS, Yongchao G, Edelmann L, Bahieg S, Raynal P, Flex E, Tartaglia M, Moore KA, Lemischka IR, Gelb BD. Mulero-Navarro S, et al. Among authors: sevilla a. Cell Rep. 2015 Oct 20;13(3):504-515. doi: 10.1016/j.celrep.2015.09.019. Epub 2015 Oct 8. Cell Rep. 2015. PMID: 26456833 Free PMC article.
136 results