Sachais BS - Search Results

1

Rational design and characterization of platelet factor 4 antagonists for the study of heparin-induced thrombocytopenia.

Sachais BS, Rux AH, Cines DB, Yarovoi SV, Garner LI, Watson SP, Hinds JL, Rux JJ. Sachais BS, et al. Blood. 2012 Jun 21;119(25):5955-62. doi: 10.1182/blood-2012-01-406801. Epub 2012 Mar 27. Blood. 2012. PMID: 22452981 Free PMC article.

2

Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic machinery, resulting in retention of low-density lipoprotein on the cell surface.

Sachais BS, Kuo A, Nassar T, Morgan J, Kariko K, Williams KJ, Feldman M, Aviram M, Shah N, Jarett L, Poncz M, Cines DB, Higazi AA. Sachais BS, et al. Blood. 2002 May 15;99(10):3613-22. doi: 10.1182/blood.v99.10.3613. Blood. 2002. PMID: 11986215 Free article.

3

Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia.

Rauova L, Poncz M, McKenzie SE, Reilly MP, Arepally G, Weisel JW, Nagaswami C, Cines DB, Sachais BS. Rauova L, et al. Among authors: sachais bs. Blood. 2005 Jan 1;105(1):131-8. doi: 10.1182/blood-2004-04-1544. Epub 2004 Aug 10. Blood. 2005. PMID: 15304392 Free article.

4

Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-kappaB-dependent manner.

Yu G, Rux AH, Ma P, Bdeir K, Sachais BS. Yu G, et al. Among authors: sachais bs. Blood. 2005 May 1;105(9):3545-51. doi: 10.1182/blood-2004-07-2617. Epub 2004 Dec 9. Blood. 2005. PMID: 15591119 Free PMC article.

5

Heparin-induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly.

Cines DB, Rauova L, Arepally G, Reilly MP, McKenzie SE, Sachais BS, Poncz M. Cines DB, et al. Among authors: sachais bs. J Clin Apher. 2007 Feb;22(1):31-6. doi: 10.1002/jca.20109. J Clin Apher. 2007. PMID: 17285619 Review.

6

Low-density lipoprotein apheresis reduces platelet factor 4 on the surface of platelets: a possible protective mechanism against heparin-induced thrombocytopenia and thrombosis.

Tanhehco YC, Rux AH, Sachais BS. Tanhehco YC, et al. Among authors: sachais bs. Transfusion. 2011 May;51(5):1022-9. doi: 10.1111/j.1537-2995.2010.02911.x. Epub 2010 Oct 26. Transfusion. 2011. PMID: 20977482 Free PMC article. Clinical Trial.

7

Dynamic antibody-binding properties in the pathogenesis of HIT.

Sachais BS, Litvinov RI, Yarovoi SV, Rauova L, Hinds JL, Rux AH, Arepally GM, Poncz M, Cuker A, Weisel JW, Cines DB. Sachais BS, et al. Blood. 2012 Aug 2;120(5):1137-42. doi: 10.1182/blood-2012-01-407262. Epub 2012 May 10. Blood. 2012. PMID: 22577175 Free PMC article.

8

Antigen and substrate withdrawal in the management of autoimmune thrombotic disorders.

Cines DB, McCrae KR, Zheng XL, Sachais BS, Luning Prak ET, Siegel DL. Cines DB, et al. Among authors: sachais bs. Blood. 2012 Nov 15;120(20):4134-42. doi: 10.1182/blood-2012-06-389445. Epub 2012 Sep 10. Blood. 2012. PMID: 22966172 Free PMC article. Review.

9

Novel diagnostic assays for heparin-induced thrombocytopenia.

Cuker A, Rux AH, Hinds JL, Dela Cruz M, Yarovoi SV, Brown IA, Yang W, Konkle BA, Arepally GM, Watson SP, Cines DB, Sachais BS. Cuker A, et al. Among authors: sachais bs. Blood. 2013 May 2;121(18):3727-32. doi: 10.1182/blood-2013-01-479576. Epub 2013 Feb 27. Blood. 2013. PMID: 23446735 Free PMC article.

10

Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA.

Reilly MP, Taylor SM, Hartman NK, Arepally GM, Sachais BS, Cines DB, Poncz M, McKenzie SE. Reilly MP, et al. Among authors: sachais bs. Blood. 2001 Oct 15;98(8):2442-7. doi: 10.1182/blood.v98.8.2442. Blood. 2001. PMID: 11588041 Free article.

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