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Aging, atherosclerosis, and IGF-1.
Higashi Y, Sukhanov S, Anwar A, Shai SY, Delafontaine P. Higashi Y, et al. Among authors: shai sy. J Gerontol A Biol Sci Med Sci. 2012 Jun;67(6):626-39. doi: 10.1093/gerona/gls102. Epub 2012 Apr 5. J Gerontol A Biol Sci Med Sci. 2012. PMID: 22491965 Free PMC article. Review.
IGF-1, oxidative stress and atheroprotection.
Higashi Y, Sukhanov S, Anwar A, Shai SY, Delafontaine P. Higashi Y, et al. Among authors: shai sy. Trends Endocrinol Metab. 2010 Apr;21(4):245-54. doi: 10.1016/j.tem.2009.12.005. Epub 2010 Jan 12. Trends Endocrinol Metab. 2010. PMID: 20071192 Free PMC article. Review.
Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA.
Blackstock CD, Higashi Y, Sukhanov S, Shai SY, Stefanovic B, Tabony AM, Yoshida T, Delafontaine P. Blackstock CD, et al. Among authors: shai sy. J Biol Chem. 2014 Mar 14;289(11):7264-74. doi: 10.1074/jbc.M113.518951. Epub 2014 Jan 27. J Biol Chem. 2014. PMID: 24469459 Free PMC article.
Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice.
Higashi Y, Sukhanov S, Shai SY, Danchuk S, Tang R, Snarski P, Li Z, Lobelle-Rich P, Wang M, Wang D, Yu H, Korthuis R, Delafontaine P. Higashi Y, et al. Among authors: shai sy. Circulation. 2016 Jun 7;133(23):2263-78. doi: 10.1161/CIRCULATIONAHA.116.021805. Epub 2016 May 6. Circulation. 2016. PMID: 27154724 Free PMC article.
30 results