Singh P - Search Results

1

Progastrin overexpression imparts tumorigenic/metastatic potential to embryonic epithelial cells: phenotypic differences between transformed and nontransformed stem cells.

Sarkar S, Kantara C, Ortiz I, Swiercz R, Kuo J, Davey R, Escobar K, Ullrich R, Singh P. Sarkar S, et al. Among authors: singh p. Int J Cancer. 2012 Oct 1;131(7):E1088-99. doi: 10.1002/ijc.27615. Epub 2012 May 17. Int J Cancer. 2012. PMID: 22532325 Free PMC article.

2

Gastrin gene expression is required for the proliferation and tumorigenicity of human colon cancer cells.

Singh P, Owlia A, Varro A, Dai B, Rajaraman S, Wood T. Singh P, et al. Cancer Res. 1996 Sep 15;56(18):4111-5. Cancer Res. 1996. PMID: 8797575

3

Intestinal expression of mutant and wild-type progastrin significantly increases colon carcinogenesis in response to azoxymethane in transgenic mice.

Cobb S, Wood T, Ceci J, Varro A, Velasco M, Singh P. Cobb S, et al. Among authors: singh p. Cancer. 2004 Mar 15;100(6):1311-23. doi: 10.1002/cncr.20094. Cancer. 2004. PMID: 15022301 Free article.

4

Annexin II binds progastrin and gastrin-like peptides, and mediates growth factor effects of autocrine and exogenous gastrins on colon cancer and intestinal epithelial cells.

Singh P, Wu H, Clark C, Owlia A. Singh P, et al. Oncogene. 2007 Jan 18;26(3):425-40. doi: 10.1038/sj.onc.1209798. Epub 2006 Jul 10. Oncogene. 2007. PMID: 16832341

5

Role of Annexin-II in GI cancers: interaction with gastrins/progastrins.

Singh P. Singh P. Cancer Lett. 2007 Jul 8;252(1):19-35. doi: 10.1016/j.canlet.2006.11.012. Epub 2006 Dec 22. Cancer Lett. 2007. PMID: 17188424 Free PMC article. Review.

Wu, G.N. Rao, B. Dai, P. Singh, Autocrine gastrins in colon cancer cells Up-regulate cytochrome c oxidase Vb and down-regulate efflux of cytochrome c and activation of caspase-3, J. ...Several receptor subtypes have been described that mediate growth effects of gast …

Wu, G.N. Rao, B. Dai, P. Singh, Autocrine gastrins in colon cancer cells Up-regulate cytochrome c oxidase Vb and down-regulate …

6

Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B.

Rengifo-Cam W, Umar S, Sarkar S, Singh P. Rengifo-Cam W, et al. Among authors: singh p. Cancer Res. 2007 Aug 1;67(15):7266-74. doi: 10.1158/0008-5472.CAN-07-1206. Cancer Res. 2007. PMID: 17671195

7

Activation of NF-kappaB is required for mediating proliferative and antiapoptotic effects of progastrin on proximal colonic crypts of mice, in vivo.

Umar S, Sarkar S, Cowey S, Singh P. Umar S, et al. Among authors: singh p. Oncogene. 2008 Sep 18;27(42):5599-611. doi: 10.1038/onc.2008.169. Epub 2008 Jun 2. Oncogene. 2008. PMID: 18521082 Free PMC article.

8

Functional cross-talk between beta-catenin and NFkappaB signaling pathways in colonic crypts of mice in response to progastrin.

Umar S, Sarkar S, Wang Y, Singh P. Umar S, et al. Among authors: singh p. J Biol Chem. 2009 Aug 14;284(33):22274-22284. doi: 10.1074/jbc.M109.020941. Epub 2009 Jun 4. J Biol Chem. 2009. PMID: 19497850 Free PMC article.

9

Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.

Singh P, Sarkar S, Umar S, Rengifo-Cam W, Singh AP, Wood TG. Singh P, et al. Among authors: singh ap. Am J Physiol Gastrointest Liver Physiol. 2010 Apr;298(4):G551-62. doi: 10.1152/ajpgi.00497.2009. Epub 2010 Feb 4. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 20133951 Free PMC article.

10

Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38.

Chandrakesan P, Ahmed I, Anwar T, Wang Y, Sarkar S, Singh P, Peleg S, Umar S. Chandrakesan P, et al. Among authors: singh p. J Biol Chem. 2010 Oct 22;285(43):33485-33498. doi: 10.1074/jbc.M110.129353. Epub 2010 Aug 14. J Biol Chem. 2010. PMID: 20710027 Free PMC article.

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