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454 results

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Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist.
Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. Iwaisako K, et al. Among authors: brenner da. Proc Natl Acad Sci U S A. 2012 May 22;109(21):E1369-76. doi: 10.1073/pnas.1202464109. Epub 2012 Apr 25. Proc Natl Acad Sci U S A. 2012. PMID: 22538808 Free PMC article.
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis.
Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA. Kisseleva T, et al. Among authors: brenner da. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9448-53. doi: 10.1073/pnas.1201840109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566629 Free PMC article.
Origin of myofibroblasts in the fibrotic liver in mice.
Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA, Hofmann AF, Iida T, Glass CK, Brenner DA, Kisseleva T. Iwaisako K, et al. Among authors: brenner da. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3297-305. doi: 10.1073/pnas.1400062111. Epub 2014 Jul 29. Proc Natl Acad Sci U S A. 2014. PMID: 25074909 Free PMC article.
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity.
Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, Evans RM, Brenner DA, Saltiel AR, Beutler B, Schnabl B. Wang L, et al. Among authors: brenner da. Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15184-15193. doi: 10.1073/pnas.1904360116. Epub 2019 Jul 9. Proc Natl Acad Sci U S A. 2019. PMID: 31289229 Free PMC article.
Immunotherapy-based targeting of MSLN+ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis.
Nishio T, Koyama Y, Liu X, Rosenthal SB, Yamamoto G, Fuji H, Baglieri J, Li N, Brenner LN, Iwaisako K, Taura K, Hagood JS, LaRusso NF, Bera TK, Pastan I, Brenner DA, Kisseleva T. Nishio T, et al. Among authors: brenner ln, brenner da. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2101270118. doi: 10.1073/pnas.2101270118. Proc Natl Acad Sci U S A. 2021. PMID: 34253615 Free PMC article.
454 results