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HDL-like discs for assaying membrane proteins in drug discovery.
Fiez-Vandal C, Leder L, Freuler F, Sykes D, Charlton SJ, Siehler S, Schopfer U, Duckely M. Fiez-Vandal C, et al. Among authors: siehler s. Biophys Chem. 2012 May;165-166:56-61. doi: 10.1016/j.bpc.2012.03.005. Epub 2012 Mar 19. Biophys Chem. 2012. PMID: 22542136
High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor.
Groot-Kormelink PJ, Ferrand S, Kelley N, Bill A, Freuler F, Imbert PE, Marelli A, Gerwin N, Sivilotti LG, Miraglia L, Orth AP, Oakeley EJ, Schopfer U, Siehler S. Groot-Kormelink PJ, et al. Among authors: siehler s. PLoS One. 2016 Sep 20;11(9):e0163129. doi: 10.1371/journal.pone.0163129. eCollection 2016. PLoS One. 2016. PMID: 27649498 Free PMC article.
Cell-based assays in GPCR drug discovery.
Siehler S. Siehler S. Biotechnol J. 2008 Apr;3(4):471-83. doi: 10.1002/biot.200800001. Biotechnol J. 2008. PMID: 18383022 Review.
32 results