Hwang JW - Search Results

1

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice.

Yao H, Chung S, Hwang JW, Rajendrasozhan S, Sundar IK, Dean DA, McBurney MW, Guarente L, Gu W, Rönty M, Kinnula VL, Rahman I. Yao H, et al. Among authors: hwang jw. J Clin Invest. 2012 Jun;122(6):2032-45. doi: 10.1172/JCI60132. Epub 2012 May 1. J Clin Invest. 2012. PMID: 22546858 Free PMC article.

2

PARP-1 inhibition does not restore oxidant-mediated reduction in SIRT1 activity.

Caito S, Hwang JW, Chung S, Yao H, Sundar IK, Rahman I. Caito S, et al. Among authors: hwang jw. Biochem Biophys Res Commun. 2010 Feb 12;392(3):264-70. doi: 10.1016/j.bbrc.2009.12.161. Epub 2010 Jan 10. Biochem Biophys Res Commun. 2010. PMID: 20060806 Free PMC article.

3

Regulation of SIRT1 in cellular functions: role of polyphenols.

Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I. Chung S, et al. Among authors: hwang jw. Arch Biochem Biophys. 2010 Sep 1;501(1):79-90. doi: 10.1016/j.abb.2010.05.003. Epub 2010 May 5. Arch Biochem Biophys. 2010. PMID: 20450879 Free PMC article. Review.

4

Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD.

Hwang JW, Chung S, Sundar IK, Yao H, Arunachalam G, McBurney MW, Rahman I. Hwang JW, et al. Arch Biochem Biophys. 2010 Aug 15;500(2):203-9. doi: 10.1016/j.abb.2010.05.013. Epub 2010 May 20. Arch Biochem Biophys. 2010. PMID: 20493163 Free PMC article.

5

Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM.

Yao H, Arunachalam G, Hwang JW, Chung S, Sundar IK, Kinnula VL, Crapo JD, Rahman I. Yao H, et al. Among authors: hwang jw. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15571-6. doi: 10.1073/pnas.1007625107. Epub 2010 Aug 16. Proc Natl Acad Sci U S A. 2010. PMID: 20713693 Free PMC article.

6

Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation.

Sundar IK, Hwang JW, Wu S, Sun J, Rahman I. Sundar IK, et al. Among authors: hwang jw. Biochem Biophys Res Commun. 2011 Mar 4;406(1):127-33. doi: 10.1016/j.bbrc.2011.02.011. Epub 2011 Feb 12. Biochem Biophys Res Commun. 2011. PMID: 21300024 Free PMC article.

7

FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease.

Hwang JW, Rajendrasozhan S, Yao H, Chung S, Sundar IK, Huyck HL, Pryhuber GS, Kinnula VL, Rahman I. Hwang JW, et al. J Immunol. 2011 Jul 15;187(2):987-98. doi: 10.4049/jimmunol.1001861. Epub 2011 Jun 20. J Immunol. 2011. PMID: 21690325 Free PMC article.

8

NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.

Chung S, Sundar IK, Hwang JW, Yull FE, Blackwell TS, Kinnula VL, Bulger M, Yao H, Rahman I. Chung S, et al. Among authors: hwang jw. PLoS One. 2011;6(8):e23488. doi: 10.1371/journal.pone.0023488. Epub 2011 Aug 24. PLoS One. 2011. PMID: 21887257 Free PMC article.

9

Redox regulation of SIRT1 in inflammation and cellular senescence.

Hwang JW, Yao H, Caito S, Sundar IK, Rahman I. Hwang JW, et al. Free Radic Biol Med. 2013 Aug;61:95-110. doi: 10.1016/j.freeradbiomed.2013.03.015. Epub 2013 Mar 27. Free Radic Biol Med. 2013. PMID: 23542362 Free PMC article. Review.

10

Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway.

Hwang JW, Sundar IK, Yao H, Sellix MT, Rahman I. Hwang JW, et al. FASEB J. 2014 Jan;28(1):176-94. doi: 10.1096/fj.13-232629. Epub 2013 Sep 11. FASEB J. 2014. PMID: 24025728 Free PMC article.

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