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Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase γ inhibitors.
J Med Chem. 2012 Jun 14;55(11):5467-82. doi: 10.1021/jm300403a. Epub 2012 May 17.
J Med Chem. 2012.
PMID: 22548342
SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors.
Forsyth T, Kearney PC, Kim BG, Johnson HW, Aay N, Arcalas A, Brown DS, Chan V, Chen J, Du H, Epshteyn S, Galan AA, Huynh TP, Ibrahim MA, Kane B, Koltun ES, Mann G, Meyr LE, Lee MS, Lewis GL, Noguchi RT, Pack M, Ridgway BH, Shi X, Takeuchi CS, Zu P, Leahy JW, Nuss JM, Aoyama R, Engst S, Gendreau SB, Kassees R, Li J, Lin SH, Martini JF, Stout T, Tong P, Woolfrey J, Zhang W, Yu P.
Forsyth T, et al.
Bioorg Med Chem Lett. 2012 Dec 15;22(24):7653-8. doi: 10.1016/j.bmcl.2012.10.007. Epub 2012 Oct 16.
Bioorg Med Chem Lett. 2012.
PMID: 23127890
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Synthesis and Electrochemical Studies of a Series of Fluorinated Dodecaphenylporphyrins.
Kadish KM, Van Caemelbecke E, D'Souza F, Lin M, Nurco DJ, Medforth CJ, Forsyth TP, Krattinger B, Smith KM, Fukuzumi S, Nakanishi I, Shelnutt JA.
Kadish KM, et al. Among authors: forsyth tp.
Inorg Chem. 1999 May 3;38(9):2188-2198. doi: 10.1021/ic9811695.
Inorg Chem. 1999.
PMID: 11671005
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Comparative Analysis of the Conformations of Symmetrically and Asymmetrically Deca- and Undecasubstituted Porphyrins Bearing Meso-Alkyl or -Aryl Groups.
Senge MO, Medforth CJ, Forsyth TP, Lee DA, Olmstead MM, Jentzen W, Pandey RK, Shelnutt JA, Smith KM.
Senge MO, et al. Among authors: forsyth tp.
Inorg Chem. 1997 Mar 12;36(6):1149-1163. doi: 10.1021/ic961156w.
Inorg Chem. 1997.
PMID: 11669682
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Synthesis of boronic acid analogues of alpha-amino acids by introducing side chains as electrophiles.
Jagannathan S, Forsyth TP, Kettner CA.
Jagannathan S, et al. Among authors: forsyth tp.
J Org Chem. 2001 Sep 21;66(19):6375-80. doi: 10.1021/jo015753y.
J Org Chem. 2001.
PMID: 11559189
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