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Drugging Wnt signalling in cancer.
Polakis P. Polakis P. EMBO J. 2012 Jun 13;31(12):2737-46. doi: 10.1038/emboj.2012.126. Epub 2012 May 22. EMBO J. 2012. PMID: 22617421 Free PMC article. Review.
Wnt signaling in cancer.
Polakis P. Polakis P. Cold Spring Harb Perspect Biol. 2012 May 1;4(5):a008052. doi: 10.1101/cshperspect.a008052. Cold Spring Harb Perspect Biol. 2012. PMID: 22438566 Free PMC article. Review.
The many ways of Wnt in cancer.
Polakis P. Polakis P. Curr Opin Genet Dev. 2007 Feb;17(1):45-51. doi: 10.1016/j.gde.2006.12.007. Curr Opin Genet Dev. 2007. PMID: 17208432 Review.
Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid.
Szeto W, Jiang W, Tice DA, Rubinfeld B, Hollingshead PG, Fong SE, Dugger DL, Pham T, Yansura DG, Wong TA, Grimaldi JC, Corpuz RT, Singh JS, Frantz GD, Devaux B, Crowley CW, Schwall RH, Eberhard DA, Rastelli L, Polakis P, Pennica D. Szeto W, et al. Among authors: polakis p. Cancer Res. 2001 May 15;61(10):4197-205. Cancer Res. 2001. PMID: 11358845
Wnt signaling and cancer.
Polakis P. Polakis P. Genes Dev. 2000 Aug 1;14(15):1837-51. Genes Dev. 2000. PMID: 10921899 Free article. Review. No abstract available.
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling.
Huang X, McGann JC, Liu BY, Hannoush RN, Lill JR, Pham V, Newton K, Kakunda M, Liu J, Yu C, Hymowitz SG, Hongo JA, Wynshaw-Boris A, Polakis P, Harland RM, Dixit VM. Huang X, et al. Among authors: polakis p. Science. 2013 Mar 22;339(6126):1441-5. doi: 10.1126/science.1232253. Epub 2013 Jan 31. Science. 2013. PMID: 23371553 Free PMC article.
A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M. Lau T, et al. Among authors: polakis p. Cancer Res. 2013 May 15;73(10):3132-44. doi: 10.1158/0008-5472.CAN-12-4562. Epub 2013 Mar 28. Cancer Res. 2013. PMID: 23539443
123 results