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Novel single-chain antibody-targeted microbubbles for molecular ultrasound imaging of thrombosis: validation of a unique noninvasive method for rapid and sensitive detection of thrombi and monitoring of success or failure of thrombolysis in mice.
Wang X, Hagemeyer CE, Hohmann JD, Leitner E, Armstrong PC, Jia F, Olschewski M, Needles A, Peter K, Ahrens I. Wang X, et al. Among authors: ahrens i. Circulation. 2012 Jun 26;125(25):3117-26. doi: 10.1161/CIRCULATIONAHA.111.030312. Epub 2012 May 30. Circulation. 2012. PMID: 22647975
Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets.
Wang X, Palasubramaniam J, Gkanatsas Y, Hohmann JD, Westein E, Kanojia R, Alt K, Huang D, Jia F, Ahrens I, Medcalf RL, Peter K, Hagemeyer CE. Wang X, et al. Among authors: ahrens i. Circ Res. 2014 Mar 28;114(7):1083-93. doi: 10.1161/CIRCRESAHA.114.302514. Epub 2014 Feb 9. Circ Res. 2014. PMID: 24508759
Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongation.
Stoll P, Bassler N, Hagemeyer CE, Eisenhardt SU, Chen YC, Schmidt R, Schwarz M, Ahrens I, Katagiri Y, Pannen B, Bode C, Peter K. Stoll P, et al. Among authors: ahrens i. Arterioscler Thromb Vasc Biol. 2007 May;27(5):1206-12. doi: 10.1161/ATVBAHA.106.138875. Epub 2007 Feb 22. Arterioscler Thromb Vasc Biol. 2007. PMID: 17322097
Humanizing mouse thrombi.
Ahrens I, Peter K. Ahrens I, et al. Nat Biotechnol. 2008 Jan;26(1):62-3. doi: 10.1038/nbt0108-62. Nat Biotechnol. 2008. PMID: 18183019 Review. No abstract available.
Platelet-Targeted Delivery of Peripheral Blood Mononuclear Cells to the Ischemic Heart Restores Cardiac Function after Ischemia-Reperfusion Injury.
Ziegler M, Wang X, Lim B, Leitner E, Klingberg F, Ching V, Yao Y, Huang D, Gao XM, Kiriazis H, Du XJ, Haigh JJ, Bobik A, Hagemeyer CE, Ahrens I, Peter K. Ziegler M, et al. Among authors: ahrens i. Theranostics. 2017 Jul 22;7(13):3192-3206. doi: 10.7150/thno.19698. eCollection 2017. Theranostics. 2017. PMID: 28900504 Free PMC article.
Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques.
Eisenhardt SU, Habersberger J, Murphy A, Chen YC, Woollard KJ, Bassler N, Qian H, von Zur Muhlen C, Hagemeyer CE, Ahrens I, Chin-Dusting J, Bobik A, Peter K. Eisenhardt SU, et al. Among authors: ahrens i. Circ Res. 2009 Jul 17;105(2):128-37. doi: 10.1161/CIRCRESAHA.108.190611. Epub 2009 Jun 11. Circ Res. 2009. PMID: 19520972
123 results