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[COPD: An early disease].
Margelidon-Cozzolino V, Chbini K, Freymond N, Devouassoux G, Belaaouaj A, Pacheco Y. Margelidon-Cozzolino V, et al. Among authors: belaaouaj a. Rev Pneumol Clin. 2016 Feb;72(1):49-60. doi: 10.1016/j.pneumo.2015.08.002. Epub 2015 Dec 3. Rev Pneumol Clin. 2016. PMID: 26657351 Free PMC article. Review. French.
Triterpenoids as neutrophil elastase inhibitors.
Guillaume D, Huynh TN, Clément Denhez, Nguyen KP, Belaaouaj A. Guillaume D, et al. Among authors: belaaouaj a. Nat Prod Commun. 2015 Jan;10(1):167-70. Nat Prod Commun. 2015. PMID: 25920241 Review.
Neutrophil elastase-mediated increase in airway temperature during inflammation.
Schmidt A, Belaaouaj A, Bissinger R, Koller G, Malleret L, D'Orazio C, Facchinelli M, Schulte-Hubbert B, Molinaro A, Holst O, Hammermann J, Schniederjans M, Meyer KC, Damkiaer S, Piacentini G, Assael B, Bruce K, Häußler S, LiPuma JJ, Seelig J, Worlitzsch D, Döring G. Schmidt A, et al. Among authors: belaaouaj a. J Cyst Fibros. 2014 Dec;13(6):623-31. doi: 10.1016/j.jcf.2014.03.004. Epub 2014 Apr 6. J Cyst Fibros. 2014. PMID: 24713593 Free article.
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.
Gehrig S, Duerr J, Weitnauer M, Wagner CJ, Graeber SY, Schatterny J, Hirtz S, Belaaouaj A, Dalpke AH, Schultz C, Mall MA. Gehrig S, et al. Among authors: belaaouaj a. Am J Respir Crit Care Med. 2014 May 1;189(9):1082-92. doi: 10.1164/rccm.201311-1932OC. Am J Respir Crit Care Med. 2014. PMID: 24678594
Survival and differentiation defects contribute to neutropenia in glucose-6-phosphatase-β (G6PC3) deficiency in a model of mouse neutrophil granulocyte differentiation.
Gautam S, Kirschnek S, Gentle IE, Kopiniok C, Henneke P, Häcker H, Malleret L, Belaaouaj A, Häcker G. Gautam S, et al. Among authors: belaaouaj a. Cell Death Differ. 2013 Aug;20(8):1068-79. doi: 10.1038/cdd.2013.39. Epub 2013 May 17. Cell Death Differ. 2013. PMID: 23686134 Free PMC article.
Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.
Le Gars M, Descamps D, Roussel D, Saussereau E, Guillot L, Ruffin M, Tabary O, Hong SS, Boulanger P, Paulais M, Malleret L, Belaaouaj A, Edelman A, Huerre M, Chignard M, Sallenave JM. Le Gars M, et al. Among authors: belaaouaj a. Am J Respir Crit Care Med. 2013 Jan 15;187(2):170-9. doi: 10.1164/rccm.201205-0875OC. Epub 2012 Dec 6. Am J Respir Crit Care Med. 2013. PMID: 23220915
Synthesis of PDE IVb Inhibitors. 3. Synthesis of (+)-, (-)-, and (±)-7-[3-(cyclopentyloxy)-4-methoxyphenyl]hexahydro-3H-pyrrolizin-3-one via reductive domino transformations of 3-β-carbomethoxyethyl-substituted six-membered cyclic nitronates.
Sukhorukov AY, Boyko YD, Nelyubina YV, Gerard S, Ioffe SL, Tartakovsky VA, Laurette Malleret L, Belaaouaj A. Sukhorukov AY, et al. Among authors: belaaouaj a. J Org Chem. 2012 Jun 15;77(12):5465-9. doi: 10.1021/jo300955n. Epub 2012 Jun 6. J Org Chem. 2012. PMID: 22670642
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Motta JP, Magne L, Descamps D, Rolland C, Squarzoni-Dale C, Rousset P, Martin L, Cenac N, Balloy V, Huerre M, Fröhlich LF, Jenne D, Wartelle J, Belaaouaj A, Mas E, Vinel JP, Alric L, Chignard M, Vergnolle N, Sallenave JM. Motta JP, et al. Among authors: belaaouaj a. Gastroenterology. 2011 Apr;140(4):1272-82. doi: 10.1053/j.gastro.2010.12.050. Epub 2011 Jan 1. Gastroenterology. 2011. PMID: 21199654
45 results