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Structure-activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway inhibitor and anti-cancer agent.
Mun J, Jabbar AA, Devi NS, Liu Y, Van Meir EG, Goodman MM. Mun J, et al. Bioorg Med Chem. 2012 Jul 15;20(14):4590-7. doi: 10.1016/j.bmc.2012.04.064. Epub 2012 May 14. Bioorg Med Chem. 2012. PMID: 22682301 Free PMC article.
Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.
Yin S, Kaluz S, Devi NS, Jabbar AA, de Noronha RG, Mun J, Zhang Z, Boreddy PR, Wang W, Wang Z, Abbruscato T, Chen Z, Olson JJ, Zhang R, Goodman MM, Nicolaou KC, Van Meir EG. Yin S, et al. Among authors: mun j. Clin Cancer Res. 2012 Dec 15;18(24):6623-33. doi: 10.1158/1078-0432.CCR-12-0861. Epub 2012 Aug 24. Clin Cancer Res. 2012. PMID: 22923450 Free PMC article.
Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter.
Zeng F, Mun J, Jarkas N, Stehouwer JS, Voll RJ, Tamagnan GD, Howell L, Votaw JR, Kilts CD, Nemeroff CB, Goodman MM. Zeng F, et al. Among authors: mun j. J Med Chem. 2009 Jan 8;52(1):62-73. doi: 10.1021/jm800817h. J Med Chem. 2009. PMID: 19067522 Free PMC article.
Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth.
Kaluz S, Zhang Q, Kuranaga Y, Yang H, Osuka S, Bhattacharya D, Devi NS, Mun J, Wang W, Zhang R, Goodman MM, Grossniklaus HE, Van Meir EG. Kaluz S, et al. Among authors: mun j. Oncogene. 2021 Aug;40(33):5182-5191. doi: 10.1038/s41388-021-01919-x. Epub 2021 Jul 3. Oncogene. 2021. PMID: 34218269 Free PMC article.
Chronic interferon-α decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates.
Felger JC, Mun J, Kimmel HL, Nye JA, Drake DF, Hernandez CR, Freeman AA, Rye DB, Goodman MM, Howell LL, Miller AH. Felger JC, et al. Among authors: mun j. Neuropsychopharmacology. 2013 Oct;38(11):2179-87. doi: 10.1038/npp.2013.115. Epub 2013 May 9. Neuropsychopharmacology. 2013. PMID: 23657438 Free PMC article.
794 results