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Structure-activity relationship of 2,2-dimethyl-2H-chromene based arylsulfonamide analogs of 3,4-dimethoxy-N-[(2,2-dimethyl-2H-chromen-6-yl)methyl]-N-phenylbenzenesulfonamide, a novel small molecule hypoxia inducible factor-1 (HIF-1) pathway inhibitor and anti-cancer agent.
Mun J, Jabbar AA, Devi NS, Liu Y, Van Meir EG, Goodman MM. Mun J, et al. Among authors: van meir eg. Bioorg Med Chem. 2012 Jul 15;20(14):4590-7. doi: 10.1016/j.bmc.2012.04.064. Epub 2012 May 14. Bioorg Med Chem. 2012. PMID: 22682301 Free PMC article.
Inhibitors of hypoxia-inducible factor-1 signaling.
Belozerov VE, Van Meir EG. Belozerov VE, et al. Among authors: van meir eg. Curr Opin Investig Drugs. 2006 Dec;7(12):1067-76. Curr Opin Investig Drugs. 2006. PMID: 17209524 Review.
Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism.
Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG. Kaur B, et al. Among authors: van meir eg. Cancer Res. 2009 Feb 1;69(3):1212-20. doi: 10.1158/0008-5472.CAN-08-1166. Epub 2009 Jan 27. Cancer Res. 2009. PMID: 19176395 Free PMC article.
Identification of a novel small molecule HIF-1alpha translation inhibitor.
Narita T, Yin S, Gelin CF, Moreno CS, Yepes M, Nicolaou KC, Van Meir EG. Narita T, et al. Among authors: van meir eg. Clin Cancer Res. 2009 Oct 1;15(19):6128-36. doi: 10.1158/1078-0432.CCR-08-3180. Epub 2009 Sep 29. Clin Cancer Res. 2009. PMID: 19789328 Free PMC article.
274 results