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Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling.
He G, Dhar D, Nakagawa H, Font-Burgada J, Ogata H, Jiang Y, Shalapour S, Seki E, Yost SE, Jepsen K, Frazer KA, Harismendy O, Hatziapostolou M, Iliopoulos D, Suetsugu A, Hoffman RM, Tateishi R, Koike K, Karin M. He G, et al. Among authors: seki e. Cell. 2013 Oct 10;155(2):384-96. doi: 10.1016/j.cell.2013.09.031. Cell. 2013. PMID: 24120137 Free PMC article.
p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells.
Umemura A, He F, Taniguchi K, Nakagawa H, Yamachika S, Font-Burgada J, Zhong Z, Subramaniam S, Raghunandan S, Duran A, Linares JF, Reina-Campos M, Umemura S, Valasek MA, Seki E, Yamaguchi K, Koike K, Itoh Y, Diaz-Meco MT, Moscat J, Karin M. Umemura A, et al. Among authors: seki e. Cancer Cell. 2016 Jun 13;29(6):935-948. doi: 10.1016/j.ccell.2016.04.006. Epub 2016 May 19. Cancer Cell. 2016. PMID: 27211490 Free PMC article.
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR, McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, Diaz-Meco MT, Moscat J, Karin M. Zhong Z, et al. Among authors: seki e. Cell. 2016 Feb 25;164(5):896-910. doi: 10.1016/j.cell.2015.12.057. Cell. 2016. PMID: 26919428 Free PMC article.
Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.
Dhar D, Antonucci L, Nakagawa H, Kim JY, Glitzner E, Caruso S, Shalapour S, Yang L, Valasek MA, Lee S, Minnich K, Seki E, Tuckermann J, Sibilia M, Zucman-Rossi J, Karin M. Dhar D, et al. Among authors: seki e. Cancer Cell. 2018 Jun 11;33(6):1061-1077.e6. doi: 10.1016/j.ccell.2018.05.003. Cancer Cell. 2018. PMID: 29894692 Free PMC article.
Integrative genomic analysis of mouse and human hepatocellular carcinoma.
Dow M, Pyke RM, Tsui BY, Alexandrov LB, Nakagawa H, Taniguchi K, Seki E, Harismendy O, Shalapour S, Karin M, Carter H, Font-Burgada J. Dow M, et al. Among authors: seki e. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9879-E9888. doi: 10.1073/pnas.1811029115. Epub 2018 Oct 4. Proc Natl Acad Sci U S A. 2018. PMID: 30287485 Free PMC article.
247 results