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Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.
Kiss J, Mollenhauer M, Walmsley SR, Kirchberg J, Radhakrishnan P, Niemietz T, Dudda J, Steinert G, Whyte MK, Carmeliet P, Mazzone M, Weitz J, Schneider M. Kiss J, et al. Among authors: radhakrishnan p. J Immunol. 2012 Aug 15;189(4):1955-65. doi: 10.4049/jimmunol.1103471. Epub 2012 Jul 11. J Immunol. 2012. PMID: 22786772 Free PMC article.
Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro.
Kahlert C, Lahes S, Radhakrishnan P, Dutta S, Mogler C, Herpel E, Brand K, Steinert G, Schneider M, Mollenhauer M, Reissfelder C, Klupp F, Fritzmann J, Wunder C, Benner A, Kloor M, Huth C, Contin P, Ulrich A, Koch M, Weitz J. Kahlert C, et al. Among authors: radhakrishnan p. Clin Cancer Res. 2011 Dec 15;17(24):7654-63. doi: 10.1158/1078-0432.CCR-10-2816. Epub 2011 Oct 31. Clin Cancer Res. 2011. PMID: 22042972
PHD1 regulates p53-mediated colorectal cancer chemoresistance.
Deschoemaeker S, Di Conza G, Lilla S, Martín-Pérez R, Mennerich D, Boon L, Hendrikx S, Maddocks OD, Marx C, Radhakrishnan P, Prenen H, Schneider M, Myllyharju J, Kietzmann T, Vousden KH, Zanivan S, Mazzone M. Deschoemaeker S, et al. Among authors: radhakrishnan p. EMBO Mol Med. 2015 Oct;7(10):1350-65. doi: 10.15252/emmm.201505492. EMBO Mol Med. 2015. PMID: 26290450 Free PMC article.
Bcl-xL is an oncogenic driver in colorectal cancer.
Scherr AL, Gdynia G, Salou M, Radhakrishnan P, Duglova K, Heller A, Keim S, Kautz N, Jassowicz A, Elssner C, He YW, Jaeger D, Heikenwalder M, Schneider M, Weber A, Roth W, Schulze-Bergkamen H, Koehler BC. Scherr AL, et al. Among authors: radhakrishnan p. Cell Death Dis. 2016 Aug 18;7(8):e2342. doi: 10.1038/cddis.2016.233. Cell Death Dis. 2016. PMID: 27537525 Free PMC article.
LDB1 overexpression is a negative prognostic factor in colorectal cancer.
García SA, Swiersy A, Radhakrishnan P, Branchi V, Kanth Nanduri L, Győrffy B, Betzler AM, Bork U, Kahlert C, Reißfelder C, Rahbari NN, Weitz J, Schölch S. García SA, et al. Among authors: radhakrishnan p. Oncotarget. 2016 Dec 20;7(51):84258-84270. doi: 10.18632/oncotarget.12481. Oncotarget. 2016. PMID: 27713177 Free PMC article.
Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected].
Manresa MC, Tambuwala MM, Radhakrishnan P, Harnoss JM, Brown E, Cavadas MA, Keogh CE, Cheong A, Barrett KE, Cummins EP, Schneider M, Taylor CT. Manresa MC, et al. Among authors: radhakrishnan p. Am J Physiol Gastrointest Liver Physiol. 2016 Dec 1;311(6):G1076-G1090. doi: 10.1152/ajpgi.00229.2016. Epub 2016 Oct 27. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27789456 Free article.
206 results