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Heparin disrupts the CXCR4/SDF-1 axis and impairs the functional capacity of bone marrow-derived mononuclear cells used for cardiovascular repair.
Seeger FH, Rasper T, Fischer A, Muhly-Reinholz M, Hergenreider E, Leistner DM, Sommer K, Manavski Y, Henschler R, Chavakis E, Assmus B, Zeiher AM, Dimmeler S. Seeger FH, et al. Among authors: chavakis e. Circ Res. 2012 Sep 14;111(7):854-62. doi: 10.1161/CIRCRESAHA.112.265678. Epub 2012 Jul 19. Circ Res. 2012. PMID: 22821930
Caspase-8 is involved in neovascularization-promoting progenitor cell functions.
Scharner D, Rössig L, Carmona G, Chavakis E, Urbich C, Fischer A, Kang TB, Wallach D, Chiang YJ, Deribe YL, Dikic I, Zeiher AM, Dimmeler S. Scharner D, et al. Among authors: chavakis e. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):571-8. doi: 10.1161/ATVBAHA.108.182006. Epub 2009 Jan 2. Arterioscler Thromb Vasc Biol. 2009. PMID: 19122169
Homing of progenitor cells to ischemic tissues.
Chavakis E, Dimmeler S. Chavakis E, et al. Antioxid Redox Signal. 2011 Aug 15;15(4):967-80. doi: 10.1089/ars.2010.3582. Epub 2011 Feb 3. Antioxid Redox Signal. 2011. PMID: 20812875 Review.
The polarity protein Scrib is essential for directed endothelial cell migration.
Michaelis UR, Chavakis E, Kruse C, Jungblut B, Kaluza D, Wandzioch K, Manavski Y, Heide H, Santoni MJ, Potente M, Eble JA, Borg JP, Brandes RP. Michaelis UR, et al. Among authors: chavakis e. Circ Res. 2013 Mar 15;112(6):924-34. doi: 10.1161/CIRCRESAHA.112.300592. Epub 2013 Jan 29. Circ Res. 2013. PMID: 23362312
41 results