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IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition.
Ropelle ER, Flores MB, Cintra DE, Rocha GZ, Pauli JR, Morari J, de Souza CT, Moraes JC, Prada PO, Guadagnini D, Marin RM, Oliveira AG, Augusto TM, Carvalho HF, Velloso LA, Saad MJ, Carvalheira JB. Ropelle ER, et al. Among authors: guadagnini d. PLoS Biol. 2010 Aug 24;8(8):e1000465. doi: 10.1371/journal.pbio.1000465. PLoS Biol. 2010. Retraction in: PLoS Biol. 2023 Apr 4;21(4):e3002079. doi: 10.1371/journal.pbio.3002079. PMID: 20808781 Free PMC article. Retracted.
Atorvastatin improves survival in septic rats: effect on tissue inflammatory pathway and on insulin signaling.
Calisto KL, Carvalho Bde M, Ropelle ER, Mittestainer FC, Camacho AC, Guadagnini D, Carvalheira JB, Saad MJ. Calisto KL, et al. Among authors: guadagnini d. PLoS One. 2010 Dec 6;5(12):e14232. doi: 10.1371/journal.pone.0014232. PLoS One. 2010. Retraction in: PLoS One. 2016 Jul 08;11(7):e0159283. doi: 10.1371/journal.pone.0159283. PMID: 21151908 Free PMC article. Retracted.
Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in tissues of DIO rats.
Oliveira AG, Carvalho BM, Tobar N, Ropelle ER, Pauli JR, Bagarolli RA, Guadagnini D, Carvalheira JB, Saad MJ. Oliveira AG, et al. Among authors: guadagnini d. Diabetes. 2011 Mar;60(3):784-96. doi: 10.2337/db09-1907. Epub 2011 Jan 31. Diabetes. 2011. Retraction in: Diabetes. 2016 Apr;65(4):1124-5. doi: 10.2337/db16-rt04. PMID: 21282367 Free PMC article. Retracted.
Comment on: Ramos-Zavala et al. Effect of diacerein on insulin secretion and metabolic control in drug-naïve patients with type 2 diabetes: a randomized clinical trial. Diabetes Care 2011;34:1591-1594.
Tobar N, Oliveira AG, Guadagnini D, Bagarolli RA, Rocha GZ, Araujo TG, Prada PO, Saad MJ. Tobar N, et al. Among authors: guadagnini d. Diabetes Care. 2012 Feb;35(2):e13; author reply e14. doi: 10.2337/dc11-1856. Diabetes Care. 2012. PMID: 22275450 Free PMC article. No abstract available.
Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice.
Carvalho-Filho MA, Carvalho BM, Oliveira AG, Guadagnini D, Ueno M, Dias MM, Tsukumo DM, Hirabara SM, Reis LF, Curi R, Carvalheira JB, Saad MJ. Carvalho-Filho MA, et al. Among authors: guadagnini d. Endocrinology. 2012 Nov;153(11):5261-74. doi: 10.1210/en.2012-1400. Epub 2012 Sep 4. Endocrinology. 2012. PMID: 22948222
57 results