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Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces.
Zhao G, Ke D, Vu T, Ahn J, Shah VB, Yang R, Aiken C, Charlton LM, Gronenborn AM, Zhang P. Zhao G, et al. Among authors: aiken c. PLoS Pathog. 2011 Mar;7(3):e1002009. doi: 10.1371/journal.ppat.1002009. Epub 2011 Mar 24. PLoS Pathog. 2011. PMID: 21455494 Free PMC article.
Structural insight into HIV-1 capsid recognition by rhesus TRIM5α.
Yang H, Ji X, Zhao G, Ning J, Zhao Q, Aiken C, Gronenborn AM, Zhang P, Xiong Y. Yang H, et al. Among authors: aiken c. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18372-7. doi: 10.1073/pnas.1210903109. Epub 2012 Oct 22. Proc Natl Acad Sci U S A. 2012. PMID: 23091002 Free PMC article.
Dynamic allostery governs cyclophilin A-HIV capsid interplay.
Lu M, Hou G, Zhang H, Suiter CL, Ahn J, Byeon IJ, Perilla JR, Langmead CJ, Hung I, Gor'kov PL, Gan Z, Brey W, Aiken C, Zhang P, Schulten K, Gronenborn AM, Polenova T. Lu M, et al. Among authors: aiken c. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14617-22. doi: 10.1073/pnas.1516920112. Epub 2015 Nov 9. Proc Natl Acad Sci U S A. 2015. PMID: 26553990 Free PMC article.
Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site.
Liu C, Perilla JR, Ning J, Lu M, Hou G, Ramalho R, Himes BA, Zhao G, Bedwell GJ, Byeon IJ, Ahn J, Gronenborn AM, Prevelige PE, Rousso I, Aiken C, Polenova T, Schulten K, Zhang P. Liu C, et al. Among authors: aiken c. Nat Commun. 2016 Mar 4;7:10714. doi: 10.1038/ncomms10714. Nat Commun. 2016. PMID: 26940118 Free PMC article.
302 results