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The mitochondrial Amidoxime Reducing Component (mARC) is involved in detoxification of N-hydroxylated base analogues.
Chem Res Toxicol. 2012 Nov 19;25(11):2443-50. doi: 10.1021/tx300298m. Epub 2012 Aug 27.
Chem Res Toxicol. 2012.
PMID: 22924387
Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC).
Ott G, Plitzko B, Krischkowski C, Reichmann D, Bittner F, Mendel RR, Kunze T, Clement B, Havemeyer A.
Ott G, et al. Among authors: krischkowski c.
Chem Res Toxicol. 2014 Oct 20;27(10):1687-95. doi: 10.1021/tx500174u. Epub 2014 Sep 18.
Chem Res Toxicol. 2014.
PMID: 25170804
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