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21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctions.
Rocha SC, Pessoa MT, Neves LD, Alves SL, Silva LM, Santos HL, Oliveira SM, Taranto AG, Comar M, Gomes IV, Santos FV, Paixão N, Quintas LE, Noël F, Pereira AF, Tessis AC, Gomes NL, Moreira OC, Rincon-Heredia R, Varotti FP, Blanco G, Villar JA, Contreras RG, Barbosa LA. Rocha SC, et al. Among authors: barbosa la. PLoS One. 2014 Oct 7;9(10):e108776. doi: 10.1371/journal.pone.0108776. eCollection 2014. PLoS One. 2014. PMID: 25290152 Free PMC article.
γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na,K-ATPase activity effect.
Alves SLG, Paixão N, Ferreira LGR, Santos FRS, Neves LDR, Oliveira GC, Cortes VF, Salomé KS, Barison A, Santos FV, Cenzi G, Varotti FP, Oliveira SMF, Taranto AG, Comar M, Silva LM, Noël F, Quintas LEM, Barbosa LA, Villar JAFP. Alves SLG, et al. Among authors: barbosa la. Bioorg Med Chem. 2015 Aug 1;23(15):4397-4404. doi: 10.1016/j.bmc.2015.06.028. Epub 2015 Jun 17. Bioorg Med Chem. 2015. PMID: 26122772 Free article.
New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells.
Garcia IJP, de Oliveira GC, de Moura Valadares JM, Banfi FF, Andrade SN, Freitas TR, Dos Santos Monção Filho E, Lima Santos H, Júnior GMV, Chaves MH, de Jesus Rodrigues D, Sanchez BAM, Varotti FP, Barbosa LA. Garcia IJP, et al. Among authors: barbosa la. Steroids. 2019 Dec;152:108490. doi: 10.1016/j.steroids.2019.108490. Epub 2019 Sep 6. Steroids. 2019. PMID: 31499071
Toxicological effects of hydroxychloroquine sulfate and chloroquine diphosphate substances on the early-life stages of fish in the COVID-19 pandemic context.
Silva IF, Enes KP, Rocha GM, Varotti FP, Barbosa LA, Thomé RG, Santos HBD. Silva IF, et al. Among authors: barbosa la. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2023;58(10):825-830. doi: 10.1080/10934529.2023.2238587. Epub 2023 Jul 24. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2023. PMID: 37488813
96 results