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RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice.
Aging (Albany NY). 2012 Sep;4(9):620-35. doi: 10.18632/aging.100488.
Aging (Albany NY). 2012.
PMID: 23075607
Free PMC article.
Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin.
Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr.
Thomas RR, et al. Among authors: smigrodzki rm.
Mitochondrion. 2011 Jan;11(1):108-18. doi: 10.1016/j.mito.2010.08.004. Epub 2010 Aug 18.
Mitochondrion. 2011.
PMID: 20727424
Free PMC article.
Item in Clipboard
Mitochondrial microheteroplasmy and a theory of aging and age-related disease.
Smigrodzki RM, Khan SM.
Smigrodzki RM, et al.
Rejuvenation Res. 2005 Fall;8(3):172-98. doi: 10.1089/rej.2005.8.172.
Rejuvenation Res. 2005.
PMID: 16144471
Review.
Item in Clipboard
Cell and animal models of mtDNA biology: progress and prospects.
Khan SM, Smigrodzki RM, Swerdlow RH.
Khan SM, et al. Among authors: smigrodzki rm.
Am J Physiol Cell Physiol. 2007 Feb;292(2):C658-69. doi: 10.1152/ajpcell.00224.2006. Epub 2006 Aug 9.
Am J Physiol Cell Physiol. 2007.
PMID: 16899549
Free article.
Review.
Item in Clipboard
High frequency of mitochondrial complex I mutations in Parkinson's disease and aging.
Smigrodzki R, Parks J, Parker WD.
Smigrodzki R, et al.
Neurobiol Aging. 2004 Nov-Dec;25(10):1273-81. doi: 10.1016/j.neurobiolaging.2004.02.020.
Neurobiol Aging. 2004.
PMID: 15465623
Clinical Trial.
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Genetic algorithm for analysis of mutations in Parkinson's disease.
Smigrodzki R, Goertzel B, Pennachin C, Coelho L, Prosdocimi F, Parker WD Jr.
Smigrodzki R, et al.
Artif Intell Med. 2005 Nov;35(3):227-41. doi: 10.1016/j.artmed.2004.11.006. Epub 2005 Oct 3.
Artif Intell Med. 2005.
PMID: 16207526
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